Phytomedicine 1996-Mar
Angiotensin converting enzyme (ACE) inhibitory flavonoids from Erythroxylum laurifolium.
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
يتم حفظ الارتباط في الحافظة
الكلمات الدالة
نبذة مختصرة
In our screening program for antihypertensive properties of plants in traditional use, the 99% ethanol extract of Erythroxylum laurifoiium leaves showed interesting angiotensin converting enzyme (ACE) inhibitory activity. The activity was found to be due to proanthocyanidins or condensed tannins and the flavonoids quercetin-3-O-rhamnoside (quercitrin) (IC(50) = 0.67 mM) and kaempferol-3-O-rhamnoside (afzelin) (IC(50) = 2.8 mM). In addition, quercitrin with afzelin demonstrated in vitro synergistic ACE inhibitory activity.