[Association of hypertension, hyperglycemia, hyperlipemia with the risk of uterine leiomyomata for female staffs in railway system].

OBJECTIVE

To understand the association of uterine fibroids risk with hypertension, hyperglycemia and hyperlipemia, and provide guidelines for the prevention of uterine leiomyomata.

METHODS

A cross-sectional study was conducted in 2008 and 6164 married female staffs in Ji'nan railway system were examined. Gynecological examinations including type B ultrasonic examination and gynecological conventional check, blood pressure and fasting blood sugar, triglycerides and cholesterol were measured. The basic information and medical history of subjects were collected. The subjects were divided into groups with or without uterine fibroids. Logistic regression was used to estimate the odds ratio for the association of uterine fibroids with hypertension, hyperglycemia and hperlipidemia.

RESULTS

The prevalence of uterine fibroids was 20.93%, the average age was (40.07 +/- 8.20) years. The prevalence of hypertension, hyperglycemia and hyperlipemia was 8.20%, 1.82% and 10.68% respectively in this population. Hypertension was significantly associated with uterine fibroids (OR = 1.316, 95% CI 1.064- 1.627). The risk of fibroids increased 17.1% for every 10 mmHg increment of diastolic blood pressure (OR = 1.171, 95% CI 1.045 - 1.312).

CONCLUSIONS

Hypertension was an independent risk factor for uterine fibroids and the risk of fibroids increased with the rise of diastolic blood pressure level.