Congenital anorchism: diagnostic and therapeutic aspects.
الكلمات الدالة
نبذة مختصرة
Eight patients with congenital anorchism were examined and treated. Plasma LH, FSH, and testosterone concentrations and the saliva testosterone level were measured by RIA in 3 patients. The results showed a 2.75 times increase in LH level, a 1.66 times increase in FSH level, and hardly measurable serum and saliva testosterone amounts. A dynamic provocating test was applied in 4 patients by Pregnyl (2000 and 4000 IU) and the results showed absence of the gonads. The semen quality control manifested a low volume of ejaculate and aspermia. Scyntiscanning of 6 patients demonstrated no functional testicular parenchyma. Substitute androgen therapy in patients with diagnosed anorchism gave good results, which suggests that this treatment is appropriate and promising. Implantation of testiculo-prostheses by using silicon alloplastic material corrects the cosmetic defect and overcomes the physiological barrier caused by the biological inferiority complex.