Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction).

Swarna Makshika (SM) is a brassy golden yellowish mineral with chemical composition of CuFeS₂ that is widely used in therapeutics to treat various disease conditions such as Prameha (diabetes), Panḍu (anemia), Kushtha (skin diseases) and Jwara (fever). This mineral needs to be processed by the following specified Ayurveda guidelines in order to make it therapeutically safe and more potent. These processes include Shodhana (preliminary process of eliminating unwanted substances), Marana (incineration) and Amritikarana (nectorization) that are mandatory and play a crucial role in therapeutics. However, till date, no published reports are available on standard manufacturing procedure of SM Shodhana.

The objective of this study is to develop the standard manufacturing procedure of SM Shodhana.

Methods described in Rasaratna Samuchhaya were followed to perform Shodhana process. Shodhana of SM was carried out in three batches (600 g in each batch) by seven quenching in Triphala Kwatha (TK, decoction of Terminalia chebula Retz., Terminalia bellirica Roxb. and Phyllanthus emblica Linn.) maintaining batch manufacturing records. Organoleptic and physicochemical analysis of media, i.e., TK and SM was carried out.

After Shodhana, golden yellowish luster of SM was completely lost and it turned into dark black coarse powder. The hardness went on decreasing and brittleness went on increasing. Average 532 g of Shodhita SM (88.67%) from 600 g of SM was obtained. Average time required for achieving red hot stage was 24.81 min. Analysis of the media revealed an increase in pH, specific gravity, and total solid contents.

The adopted method for Shodhana of 600 g of SM can be considered as easy, convenient and standard.