[The chronobiological conception of the development of acute myocardial infarction].

The subjects, 1048 patients with acute myocardial infarction (AMI), were examined in order to study the chronobiological periodicity of acute coronary catastrophes. The study established that the probability of AMI was the lowest on Sundays and Saturdays, equally higher on Mondays, Wednesdays, and Thursdays, lower on Tuesdays, and the highest on Fridays. Analysis of circannian AMI incidence demonstrates that its probability decreases in September and increases in February, March, May, and June. In August and November, the incidence of different AMI forms differs: transmural forms prevail in August, while large-focal ones prevail in November.