الصفحة 1 من عند 394 النتائج
INTRODUCTION
This invention relates generally to the field of chemotherapeutic agents and more particularly to pentapeptide heterocyclic and halophenyl amide derivatives of dolastatin 10.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate species of the Phyla Bryozoa, Molluska, and Porifera
TECHNICAL FIELD OF THE INVENTION
The present invention relates to biologically active chemical compounds, namely heteroaryl amides for treating proliferative disorders such as cancer.
BACKGROUND
Cancer is currently the second leading cause of death in the United States of America, the European Union
BACKGROUND OF THE INVENTION
Certain classes of noninfections inflammatory and hyperpigmentation diseases of the skin, thermal injuries of the skin, and premalignant skin tumors induced by ultraviolet or x-ray radiation or viruses, particularly those diseases which are multifactorial with a genetic
FIELD OF THE INVENTION
The present invention relates to a pharmaceutical composition comprising an amide derivative or its pharmaceutically acceptable salt inhibiting the growth of cancer cells and a non-metallic salt lubricant.
BACKGROUND OF THE INVENTION
The epidermal growth factor receptor (EGFR)
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/KR2012/003970 filed May 18, 2012, claiming priority based on Korean Patent Application No. 10-2011-0054685, filed Jun. 7, 2011, the contents of which are incorporated herein by reference
The invention relates to the use of pyridyl aklane, pyridyl alkene and/or pyridyl alkine acid amides, especially in the treatment of tumor conditions and/or as cytostatic agents or as immunosuppressive agents as well as medicaments with an amount of these compounds in combination with other
BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
INTRODUCTION
This invention relates generally to the field of antineoplastic compounds, and more particularly to the design and synthesis of selected tetrapeptides bearing modified phenethylamides, exhibiting tumor inhibitory effects.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate species
BACKGROUND OF THE INVENTION
Cancer is a group of diseases that are characterized by uncontrolled cell division. This uncontrolled division can compromise the function of an organism and ultimately may cause its death.
On average, in the United States, men have a 1 in 2 lifetime risk of developing
BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
FIELD OF THE INVENTION
The present invention relates to novel thiazolidinone amides, novel thiazolidine carboxylic acid amides, methods of making these compounds, and uses thereof, particularly for treating various cancers including but not limited to prostate, breast, ovarian, and skin
INTRODUCTION
This invention relates generally to the field of cancer chemotherapy and more particularly to the synthesis of unique pentapeptide amides and tetrapeptide amide derivatives of dolastatin 10 which may be useful in chemotherapy.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate
INTRODUCTION
This invention relates generally to the field of cancer chemotherapy and more particularly to the synthesis of unique pentapeptide amides and tetrapeptide amide derivatives of dolastatin 10 which may be useful in chemotherapy.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate