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الصفحة 1 من عند 19 النتائج
4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
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FIELD OF THE INVENTION
The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula
##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically
Aromatic amides
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FIELD OF THE INVENTION
This invention provides aromatic amides which are useful CNS agents, especially for treating depression, pain, anxiety, schizophrenia and seizure disorders.
BACKGROUND OF THE INVENTION
Disorders of the central nervous system have become one of the most common and most
Alkynyl amides and their therapeutic applications
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
TECHNICAL FIELD
The present invention relates to alkynyl amides, to the use of these compounds to treat seizures, migraine, and psychiatric disorders, and to the preparation of these compounds.
BACKGROUND OF THE INVENTION
Epilepsy affects roughly 1% of the world's population. Among the drugs
Biologically active amides
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
This invention is concerned with new chemicals which have valuable pharmacological properties. In particular, the invention concerns novel cinnamamides, their synthesis, pharmaceutical preparations containing them, and their use in medicine.
It has been found that the cinnamamides of formula (I), as
Use of GABA agonists for treatment of spastic disorders, convulsions, and epilepsy
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The subject invention relates to the use of gamma-aminobutyric acid (GABA) analogs and, more specifically, to the treatment of spastic disorders, convulsions, and epilepsy by administering gamma-aminobutyramide and/or any drug or compound which is broken down to yield
Imidazo(4,5-B) pyridin-2-yl amides as K.sub.V7 channel activators
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND
Potassium (K.sup.+) channels, present on the plasma membranes of most cell types, are the most diverse class of all ion channels and are associated with a wide range of physiological functions including the regulation of the electrical properties of excitable cells. The primary
Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND
Potassium (K.sup.+) channels, present on the plasma membranes of most cell types, are the most diverse class of all ion channels and are associated with a wide range of physiological functions including the regulation of the electrical properties of excitable cells. The primary
Imidazo[4,5-b]pyridin-2-yl amides as Kv7 channel activators
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND
Potassium (K+) channels, present on the plasma membranes of most cell types, are the most diverse class of all ion channels and are associated with a wide range of physiological functions including the regulation of the electrical properties of excitable cells. The primary pore-forming
N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
This invention concerns novel compounds that activate or otherwise modulate voltage-gated potassium channels. The compounds are useful for the treatment and prevention of diseases and disorders which are affected by modulation of potassium ion channels. One such condition is
Amide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
The present invention concerns novel amide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by amide derivatives. The compounds are active
Use of 5-phenyl-2-furan esters and amides as antiepileptic agents
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
This invention relates to certain novel 5-phenyl-2-furan esters and amides and the novel use of these and related compounds as antiepileptic agents.
Antiepileptic agents are used to treat seizure disorders. Approximately 2.5 million of all Americans have epilepsy.
Amide derivatives of substituted quinoxaline 2, 3-diones as glutamate receptor antagonists
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
The present invention concerns novel amide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by amide derivatives. The compounds are active
Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel imidazolone derivatives which selectively bind to GABAa receptors. More specifically it relates to substituted aryl and cycloalkyl imidazolones and to pharmaceutical compositions comprising such compounds. It
Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel imidazolone derivatives which selectively bind to GABAa receptors. More specifically it relates to substituted aryl and cycloalkyl imidazolones and to pharmaceutical compositions comprising such compounds. It
Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel imidazolone derivatives which selectively bind to GABAa receptors. More specifically it relates to substituted aryl and cycloalkyl imidazolones and to pharmaceutical compositions comprising such compounds. It
قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم
- يعمل في 55 لغة
- العلاجات العشبية مدعومة بالعلم
- التعرف على الأعشاب بالصورة
- خريطة GPS تفاعلية - ضع علامة على الأعشاب في الموقع (قريبًا)
- اقرأ المنشورات العلمية المتعلقة ببحثك
- البحث عن الأعشاب الطبية من آثارها
- نظّم اهتماماتك وابقَ على اطلاع دائم بأبحاث الأخبار والتجارب السريرية وبراءات الاختراع
اكتب أحد الأعراض أو المرض واقرأ عن الأعشاب التي قد تساعد ، واكتب عشبًا واطلع على الأمراض والأعراض التي تستخدم ضدها.
* تستند جميع المعلومات إلى البحوث العلمية المنشورة
