antithyroid/إسهال

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Graves' disease with intractable diarrhea, chylous ascites, and chylothorax: a case report.

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A 50-year-old woman was admitted to our hospital because of severe diarrhea, irritableness, and severe pitting edema of the legs. The patient had been well until 5 years before admission, when a tremor and tachycardia developed and a diagnosis of Graves' disease was made. Treatment with methimazole

Antithyroid drug-induced agranulocytosis.

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Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis. We retrospectively studied cases of

Lactose intolerance following antithyroid drug medications.

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We recently observed 2 lactase-deficient women with Graves' disease who consistently developed severe diarrhea after ingestion of thionamide (methimazole and propylthiouracil) tablets containing lactose as carrier. The strict temporal relationship between ingestion of lactose-containing tablets and

Intractable diarrhea in hyperthyroidism: management with beta-adrenergic blockade.

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OBJECTIVE To describe a patient with intractable diarrhea and thyrotoxic Graves' disease, for whom b-adrenergic blockade ultimately proved to be effective therapy for the diarrhea, and to review the types of hyperthyroidism-associated diarrhea. METHODS We present the clinical course of a young man

Neutropenic colitis with cecal perforation during antithyroid therapy.

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Neutropenic colitis, characterized by neutropenia plus cecal and ascending colon inflammation, is a rare complication of chemotherapy in hematological malignancies and, less commonly, of medication used to treat other diseases (e.g., hyperthyroidism). We report a case of neutropenic colitis with

Intractable hiccups as the presenting symptom of toxic nodular goiter.

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Hiccups differential diagnosis is a challenging one often being inconclusive and sometimes attributed to malignancies, and so of extreme importance to an internist. Seventy-five-year-old man with history of alcohol abuse, hypertension, and hyperlipidemia presented to the emergency department after

Propylthiouracil hepatitis: report of a case and extensive review of the literature.

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Antithyroid drugs (ATDs) have been widely and effectively used for the treatment of pediatric and adult thyrotoxicosis for more than a half century. Since the very beginning of ATD use, reports of hepatic dysfunction related to propylthiouracil (PTU) therapy have been published. We describe a case

Association between serum nitric oxide metabolites and thyroid hormones in a general population: Tehran Thyroid Study.

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Nitric oxide participates in the regulation of thyroid function. OBJECTIVE The purpose of this study was to determine whether there is an association between serum nitric oxide metabolites (NOx) and free thyroxine (free T4), anti-thyroid peroxidase (anti-TPO), and thyroid-stimulating hormone (TSH)

Celiac disease: presentation of 109 children.

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OBJECTIVE The clinical features of patients with celiac disease (CD) are variable. In the present study, clinical and laboratory features of 109 patients with CD were retrospectively evaluated. METHODS In all cases, diagnosis of CD was made by European Society for Paediatric Gastroenterology,

Severe starvation hypoglycemia and congestive heart failure induced by thyroid crisis, with accidentally induced severe liver dysfunction and disseminated intravascular coagulation.

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A 69-year-old woman caught a cold resulting in nausea, vomiting, diarrhea and severe anorexia. Then she suffered progressively from dyspnea and leg edema, and finally became delirious. On admission severe hypoglycemia, hypothermia, marked tachycardia, generalized edema, mild jaundice and cachexy

Unexpected causes of pulmonary hypertension in a previously healthy Thai rural man with right-sided heart failure.

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Male, 52 FINAL DIAGNOSIS: Pulmonary hypertension Symptoms: Diarrhea • dyspnea • jaundice METHODS - Clinical Procedure: - Specialty: Endocrinology and Metabolic. OBJECTIVE Unusual clinical course. BACKGROUND Hyperthyroidism is one of the important causes of high-output failure and reversible

Two cases of thyroid storm-associated cholestatic jaundice.

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OBJECTIVE To describe the association of the rare and serious complication of jaundice with severe thyrotoxicosis, a potentially lethal endocrine disorder. METHODS We report the clinical, laboratory, and pathologic findings of 2 cases of severe jaundice (total bilirubin levels: 35.2 mg/dL in case 1

Intravenous methimazole in the treatment of refractory hyperthyroidism.

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BACKGROUND Management of a hyperthyroid patient unable to take oral or rectal medication is a difficult clinical problem. The need for an alternative parenteral route of antithyroid medication administration in thyrotoxic patients occurs in certain rare cases, such as emergent gastrointestinal

Case report of Graves' disease manifesting with odynophagia and heartburn.

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Graves' disease is an autoimmune disease, which can manifest with a variety of extrathyroidal clinical syndromes like ophthalmopathy, pretibial myxedema (dermopathy), acropathy, cardiomyopathy, and encephalopathy. Though quite rare, this disease can also manifest with gastrointestinal symptoms such

Bile acid malabsorption associated with Graves' disease.

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A 40-year-old man developed dyspepsia, watery diarrhea, and weight loss. A clinical diagnosis of hyperthyroidism due to Graves' disease was confirmed [free thyroxine, 87 pmol/L (normal range, 8.6-27 pmol/L)]. Bile acid malabsorption was demonstrated by a low 23-selena-25-homocholyltauric acid

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