atherosclerosis/نيكوتين

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Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis.

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Environmental tobacco smoke (ETS) exposure and alcohol (EtOH) consumption often occur together, yet their combined effects on cardiovascular disease development are currently unclear. A shared feature between ETS and EtOH exposure is that both increase oxidative stress and dysfunction within

Impact of repeated lifestyle counselling in an atherosclerosis prevention trial on parental smoking and children's exposure to tobacco smoke.

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OBJECTIVE To determine whether repeated infancy-onset lifestyle counselling alters parental smoking and children's exposure to tobacco smoke. METHODS In 1990, 1062 healthy infants were recruited to a randomized, ongoing atherosclerosis prevention trial (STRIP). Intervention families received at

Influence of nutritional status and tobacco smoking on the development of atherosclerosis in male manual and brain workers.

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Atherosclerotic changes in the aorta and coronary arteries (stained with Sudan IV) were appraised by a visual planimetric method. The material had been obtained in a WHO-sponsored epidemiological study of atherosclerosis, carried out in Tallin, Riga, Kharkov, Ryazan, and Yalta. The authors examined

[Tobacco dependence: first risk factor of atherosclerosis. Survey among smokers and non-smokers in group dynamics].

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Several epidemiological and experimental studies have demonstrated an increased risk of atherosclerosis in smokers. The secondary prevention of this risk factor is only possible, presently, through anti-tobacco consultations. Several approaches are possible but there are many recurrences within the

Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apolipoprotein E-/- mice fed a chow diet.

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BACKGROUND Environmental tobacco smoke (ETS) exposure is recognized as a cardiovascular disease risk factor; however, the impact of prenatal ETS exposure on adult atherogenesis has not been examined. We hypothesized that in utero ETS exposure promotes adult atherosclerotic lesion formation and

Tobacco exposure-related alterations in DNA methylation and gene expression in human monocytes: the Multi-Ethnic Study of Atherosclerosis (MESA).

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Alterations in DNA methylation and gene expression in blood leukocytes are potential biomarkers of harm and mediators of the deleterious effects of tobacco exposure. However, methodological issues, including the use of self-reported smoking status and mixed cell types have made previously identified

Metoprolol does not attenuate atherosclerosis in lipid-fed rabbits exposed to environmental tobacco smoke.

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BACKGROUND We previously demonstrated that exposure to environmental tobacco smoke (ETS) increases the development of atherosclerosis in lipid-fed rabbits. Clinical studies have suggested a protective effect of beta-blockers in smokers. Accordingly, we evaluated the effects of metoprolol in this

The effects of tobacco smoke on the homocysteine level--a risk factor of atherosclerosis.

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Homocysteine may promote atherogenesis and thrombogenesis. There is evidence from case - control and cross-sectional cohort studies that there is a positive association between plasma homocysteine levels and coronary artery disease, cerebrovascular disease and peripheral vascular disease. There is

Smokeless tobacco use and atherosclerosis: an ultrasonographic investigation of carotid intima media thickness in healthy middle-aged men.

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There is well-documented evidence of accelerated atherosclerosis in smokers but the mechanisms still remain unclear. The relationship to the use of smokeless tobacco, involving high exposure to nicotine, have not been evaluated before. The possible role of nicotine was investigated in a clinical

[Effect of nicotine and tar present in cigarette smoke on the process of atherogenesis].

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Tobacco smoking is a major risk factor of the development of atherosclerosis and thrombosis. Components of tobacco smoke induce changes in the function of thrombocytes, endothelium, macrophages and smooth muscle cells of blood vessels. Smoking causes changes in activity of enzymes of antioxidant

[Tobacco smoking and obesity as risk factors of polyvascular atherosclerosis].

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The polyvascular disease is the disease that includes the simultaneous existence of atherosclerotic process on coronary, carotid and lower extremities peripheral arteries. It is very difficult, if not impossible to determine the prevalence of atherosclerosis, because it is one predominant

Nicotine in Senescence and Atherosclerosis.

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Cigarette smoke is a known exacerbator of age-related pathologies, such as cardiovascular disease (CVD), atherosclerosis, and cellular aging (senescence). However, the role of nicotine and its major metabolite cotinine is yet to be elucidated. Considering the growing amount of nicotine-containing

Carotid and femoral atherosclerosis, cardiovascular risk factors and C-reactive protein in relation to smokeless tobacco use or smoking in 58-year-old men.

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Objectives. To examine the associations between smokeless tobacco use, smoking, cardiovascular risk factors, inflammation and ultrasound-assessed measures of atherosclerosis in the carotid and femoral arteries. Subjects. The study was performed in a population-based sample of clinically healthy men

Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study.

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UNASSIGNED Cigarette smoking, various metabolic and lipid-related factors and hypertension are well-recognized cardiovascular disease (CVD) risk factors. Since smoking affects many of these factors, use of a single imprecise smoking metric, for example, ever or never smoked, may allow residual

Cigarette smoking, environmental tobacco smoke exposure and insulin sensitivity: the Insulin Resistance Atherosclerosis Study.

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OBJECTIVE To investigate whether active smoking and/or exposure to environmental tobacco smoke (ETS) is associated with insulin sensitivity. METHODS Insulin sensitivity and tobacco use history were measured in 1481 participants in the Insulin Resistance Atherosclerosis Study (IRAS). IRAS is a large

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Herbal & Natural Medicine

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