Atherosclerosis / tyrosine

Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors

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The present invention relates to a series of substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to bioisosteres of quinoline and quinazoline derivatives which exhibit protein

N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazoli n-6-yl]-acrylamide, and irreversible inhibitor of tyrosine kinases

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FIELD OF THE INVENTION This invention relates to the compound N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazol in-6-yl]-acrylamide that is an irreversible inhibitor of tyrosine kinases. This invention also relates to a method of treating cancer, atherosclerosis, restenosis,

Tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION Tyrosine kinases are a class of enzymes that catalyze the transfer of the terminal phosphate of adenosine triphospate to tyrosine residues in protein substrates. Tyrosine kinases are believed, by way of substrate phosphorylation, to play critical roles in signal

Dihydroxyindanone tyrosine kinase inhibitors

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This invention relates to dihydroxyindanone compounds which are tyrosine kinase inhibitors useful for the control of cancer, antiangiogenesis and atherosclerosis. BACKGROUND OF THE INVENTION Tyrosine-specific protein kinases (tyrosine kinases) represent a family of enzymes which catalyze the

Tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION The present invention relates to imidazopyridine compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

يمكن للمستخدمين المسجلين فقط ترجمة المقالات

الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

Tyrosine kinase inhibitors

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الدخول التسجيل فى الموقع

BACKGROUND OF THE INVENTION The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,

atherosclerosis/tyrosine

Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors

N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazoli n-6-yl]-acrylamide, and irreversible inhibitor of tyrosine kinases

Tyrosine kinase inhibitors

Dihydroxyindanone tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors

قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم