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candidiasis/سمنة

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مقالاتالتجارب السريريةبراءات الاختراع
الصفحة 1 من عند 41 النتائج

Renal Papillary Necrosis Due to Invasive Candida Infection in a Morbidly Obese Patient.

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[Candida infections in geriatrics-a current problem (author's transl)].

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Investigations for candidiasis of the skin and mucous membranes were done in 191 probands over 65 years of age, of whon 187 were occupants of an old people's home and 4 were having in-patient treatment. In the homes being tested Candida infections of the skin and mucous membranes were very numerous

Obesity and dermatology.

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Obesity is associated with a number of dermatoses. It affects cutaneous sensation, temperature regulation, foot shape, and vasculature. Acanthosis nigricans is the most common dermatological manifestation of obesity. Skin tags are more commonly associated with diabetes than with obesity. Obesity

Fractal geometry and the pharmacometrics of micafungin in overweight, obese, and extremely obese people.

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The majority of Americans are overweight, and the incidence of obesity continues to increase. This trend predisposes people to a number of deleterious consequences, including the metabolic syndrome and other conditions that lead to a greater number of hospital admissions. Invasive candidiasis is an

Morbid obesity: a chronic disease with an impact on wounds and related problems.

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Morbid obesity is a chronic disease that manifests as a steady, slow, progressive increase in body weight. Because of both emotional and physical reasons, obese people resist pursuing healthcare and may be more difficult to care for. In taking a practical approach to skin and wound care, using an

Ulcerated necrobiosis lipoidica to a teenager with diabetes mellitus and obesity.

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Many skin lesions are associated with diabetes mellitus (DM) type 1 or 2, due to the use of antidiabetics or to metabolic and endocrine disorders caused by this disease. Necrobiosis lipoidica (NL) occurs more frequently in patients with DM. Painful ulcerations may occur on NL areas in about 20-25%

Efficacy and safety of caspofungin in obese patients.

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Safety and efficacy outcomes were retrospectively compared for obese versus non-obese patients who received standard caspofungin doses for different clinical conditions in nine clinical trials within the Merck caspofungin database. Favorable outcomes were as defined in specific protocols. Safety was

Dosing of antifungal agents in obese people.

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Obesity is a worldwide epidemic associated with multiple comorbidities that increase the risk of hospitalization. Very little pharmacokinetic data are available for antifungal agents in obesity, as this population is often excluded from drug development studies and these agents are less commonly

In silico-derived bedside formula for individualized micafungin dosing for obese patients in the age of deterministic chaos.

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There are 2.1 billion people worldwide who are overweight or obese. However, most current doses of drugs were derived for normal weight patients. For several drugs, the relationship between clearance and patient weight follows fractal geometry rules. Clearance directly determines the area under the

Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients.

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BACKGROUND Dosing in obese critically ill patients is challenging due to pathophysiological changes derived from obesity and/or critical illness, and it remains fully unexplored. This study estimated the micafungin probability of reaching adequate 24-h area under the curve (AUC0-24h)/minimum

Anogenital moniliasis.

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Thirty cases of anogenital moniliasis were studied. Only five followed oral use of broad spectrum antibiotics. Although anogenital pruritus commonly follows the use of such drugs, it is rarely proved to be moniliasis, which is clinically diagnosed by symptoms of intertriginous denudation with

Evaluation of the results of treatment of morbid obesity by the endoscopic intragastric balloon implantation method.

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BACKGROUND Overweight and obesity are ranked in the fifth place among the risk factors responsible for the greatest number of deaths in the world. OBJECTIVE To assess the effects of treatment of patients with morbid obesity using endoscopic intragastric balloon (IGB) implantation. METHODS Two

Steady-state plasma pharmacokinetics of oral voriconazole in obese adults.

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Voriconazole is an antifungal agent that is currently used as primary therapy for invasive aspergillosis and as a potential treatment for systemic candidiasis. Data on the dosing of voriconazole in obese patients are not available, which is problematic given the increased prevalence of this special

The effect of obesity on skin disease and epidermal permeability barrier status in children.

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Obese adult patients have many dermatoses, such as skin tags, candida infection, cellulite, and intertrigo, but only limited data have been published on obese children and the barrier function of their skin. Sixty-five overweight and obese children (n = 40, BMI 85th-95th percentile; n = 25, BMI >

Exploring glycosuria as a mechanism for weight and fat mass reduction. A pilot study with remogliflozin etabonate and sergliflozin etabonate in healthy obese subjects.

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Inhibitors of sodium-dependent glucose co-transporter 2 (SGLT2) increase glucose excretion in the urine and improve blood glucose in Type 2 diabetes mellitus. Glycosuria provides an energy and osmotic drain that could alter body composition. We therefore conducted a pilot study comparing the effects
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