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Anti-allergic actions of the leaves of Castanea crenata and isolation of an active component responsible for the inhibition of mast cell degranulation.

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The anti-allergic actions of the leaves of Castanea crenata (Fagaceae) were studied. The water extract demonstrated potent anti-allergic actions in in vivo and in vitro experiments. The oral or intraperitoneal administration of the extract (100 or 200 mg/kg) caused a significant inhibition of the 48

Oral allergy syndrome induced by chestnut (Castanea sativa)

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BACKGROUND Oral allergy syndrome is a distinctive type of allergy to food resulting from direct contact between food and the oral mucosa. Normally, it affects patients who are allergic to pollens. It can be challenged by testing for hypersensitivity to fresh fruit or vegetables in well-known

[Severe nutritional deficiencies in young infants with inappropriate plant milk consumption].

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Over the past few years, we have observed increasing consumption of inappropriate plant milks as an alternative to infant milk formula. Some families believe that foods labeled as natural are the most healthy and an appropriate nutritional choice. However, their composition does not respect European

Airborne castanea pollen forecasting model for ecological and allergological implementation.

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Castanea sativa Miller belongs to the natural vegetation of many European deciduous forests prompting impacts in the forestry, ecology, allergological and chestnut food industry fields. The study of the Castanea flowering represents an important tool for evaluating the ecological conservation of

Purification, characterization and N-terminal amino acid sequence of a new major allergen from European chestnut pollen--Cas s 1.

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Pollens from trees of the order Fagales (e.g. birch, alder, hazel, and hornbeam) all contain one major allergen--the main cause for tree pollen allergy. So far the major allergens from birch (Bet v 1), alder (Aln g 1), hazel (Cor a 1), and hornbeam (Car b 1) have been characterized, showing high

[Sensitization to Castanea sativa pollen and pollinosis in northern Extremadura (Spain)].

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BACKGROUND Castanea sativa pollen allergy has generally been considered to be uncommon and clinically insignificant. In our geographical area (Plasencia, Cáceres, Spain) Castanea sativa pollen is a major pollen. OBJECTIVE To determine the atmospheric fluctuations and prevalence of patients

Aerobiology of sweet chestnut (Castanea sativa Mill.) in north-west Croatia.

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The aims of the study were to analyse characteristics of the Castanea airborne pollen and to compare aeropalynological data obtained from two sampling stations in north-west Croatia. The study was conducted in Zagreb and Samobor during the 2003-2006 periods, using the seven-day volumetric samplers

Allergens from birch pollen and pollen of the European chestnut share common epitopes.

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Type I allergy to pollen of the European chestnut (Castanea sativa) represents a major cause of pollinosis in (sub) Mediterranean areas. Using sera from 14 patients with established allergy to pollen of the European chestnut, 13/14 sera (92%) showed IgE-binding to a 22 kD protein, 2/14 (14%)

In vivo skin irritation potential of a Castanea sativa (Chestnut) leaf extract, a putative natural antioxidant for topical application.

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Topical application of natural antioxidants has proven to be effective in protecting the skin against ultraviolet-mediated oxidative damage and provides a straightforward way to strengthen the endogenous protection system. However, natural products can provoke skin adverse effects, such as allergic

A forecast model for hazel (Corylus) and chestnut (Castanea) pollen emission.

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In this paper a simple conceptual model is introduced in order to predict the atmospheric pollen concentration threshold above which pollinotics show allergic symptoms. In addition, the range of the pollen sampler with respect to the local and remote emission of pollen grains, produced by the

Lipid-transfer proteins as potential plant panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea nut and Rosaceae fruits, with different IgE-binding capacities.

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BACKGROUND Lipid-transfer proteins (LTPs), but not Bet v 1 homologues, have been identified as major allergens of apple and peach in the Rosaceae fruit-allergic population in the Mediterranean area. Many of these patients show cosensitization to mugwort pollen. LTPs have an ubiquitous distribution

Excavation of lead compounds that inhibit mast cell degranulation by combinatorial chemistry and activity-guided.

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An allergic reaction ensues after antigen binds to mast cell or basophil high affinity IgE receptor, Fc epsilonRI, resulting in degranulation of various inflammatory mediators that produce various allergic symptoms. In this study, i) we isolated the active component for the inhibition of mast cell

High-level expression and purification of the major birch pollen allergen, Bet v 1.

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Bet v 1, the single major allergen from birch pollen, shares IgE epitopes with all major tree pollen allergens from closely related species such as alder, hazel, hornbeam, beech, and European chestnut. Because of high sequence homologies among these allergens and the well-studied cross-reactivities

Atmospheric pollen season in Zagreb (Croatia) and its relationship with temperature and precipitation.

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The number of individuals allergic to plant pollen has recently been on a constant increase, especially in large cities and industrial areas. Therefore, monitoring of airborne pollen types and concentrations during the pollen season is of the utmost medical importance. The research reported in this

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