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chagas disease/سمنة

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مقالاتالتجارب السريريةبراءات الاختراع
الصفحة 1 من عند 28 النتائج

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model.

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الدخول التسجيل فى الموقع
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been entirely explored. A novel diet-induced obesity

The "obesity paradox" in an elderly population with a high prevalence of Chagas disease: the 10-year follow-up of the Bambuí (Brazil) Cohort Study of Aging.

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Anthropometric measures and vagal indexes of heart rate variability in a population with a high prevalence of Chagas disease--differences according to obesity status.

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Antagonistic effect of atorvastatin on high fat diet induced survival during acute Chagas disease.

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Chagasic cardiomyopathy, which is seen in Chagas disease, is the most severe and life-threatening manifestation of infection by the kinetoplastid Trypanosoma cruzi. Adipose tissue and diet play a major role in maintaining lipid homeostasis and regulating cardiac pathogenesis during the development

Metabolic syndrome agravates cardiovascular, oxidative and inflammatory dysfunction during the acute phase of Trypanosoma cruzi infection in mice.

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We evaluated the influence of metabolic syndrome (MS) on acute Trypanosoma cruzi infection. Obese Swiss mice, 70 days of age, were subjected to intraperitoneal infection with 5 × 102 trypomastigotes of the Y strain. Cardiovascular, oxidative, inflammatory, and metabolic parameters were

Advances in understanding the role of adipose tissue and mitochondrial oxidative stress in Trypanosoma cruzi infection.

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Trypanosoma cruzi, the etiologic agent of Chagas disease, causes a latent infection that results in cardiomyopathy. Infection with this pathogen is a major socio-economic burden in areas of endemic infection throughout Latin America. The development of chagasic cardiomyopathy is dependent on

[Clinical and laboratory characterization of hypertensive Chagas disease patients without evident heart failure].

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This study evaluated the characteristics of 125 Chagas disease patients aged > 25 years or over who were attended at the Clinical Hospital of the State University of Campinas, State of São Paulo. Arterial pressure, age, gender, skin color, heart disease, body mass index, lipid profile, blood glucose

Obesity and underweight among Brazilian elderly: the Bambuí Health and Aging Study.

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The coexistence of obesity (body mass index, BMI > or = 30kg/m ) and underweight (BMI <= 20kg/m ) and related factors were investigated among all residents aged 60+ years in Bambu , Minas Gerais State, using multinomial logistic regression. 1,451 (85.5%) of the town's elderly participated. Mean BMI

Metabolic, mental health, behavioural and socioeconomic characteristics of migrants with Chagas disease in a non-endemic country.

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OBJECTIVE Chronic Chagas disease causes cardiopathy in 20-40% of the 8-10 million people affected. The prevalence of atherogenic factors increases rapidly in Latin America. Somatic, mental, behavioural and social characteristics of the 80,000 Latino migrants with Chagas disease in Europe are not

Diet Quality of patients with chronic Chagas disease in a tertiary hospital: a case-control study.

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BACKGROUND Nutritional status has been implicated in the modulation of the immune response, possibly augmenting the pathogenesis of Chagas disease (Cd). We evaluated diet quality and nutritional status in adults and elderly patients with chronic Cd in a tertiary hospital. METHODS A case-control

Clinical and nutritional profile of individuals with Chagas disease.

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الدخول التسجيل فى الموقع
Chagas disease (CD), caused by the protozoan Trypanossoma cruzi, affects approximately 18 million individuals in the Americas, 5 million of which live in Brazil. Most chronic sufferers have either the indeterminate form of the disease, without organic compromise, or the cardiac or digestive forms.

The brighter (and evolutionarily older) face of the metabolic syndrome: evidence from Trypanosoma cruzi infection in CD-1 mice.

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BACKGROUND Infection with Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, results in chronic infection that leads to cardiomyopathy with increased mortality and morbidity in endemic regions. In a companion study, our group found that a high-fat diet (HFD) protected mice from T.

Association of vitamin D3, VDR gene polymorphisms, and LL-37 with a clinical form of Chagas Disease.

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Chagas disease (CD) is an important public health problem in Brazil and worldwide. Aging and obesity are important matters in patients with CD, as is hypovitaminosis D3, which can decrease the quality of life of these patients. Immunomodulation mediated by vitamin D3, especially the

Trypanosoma cruzi infection in diabetic mice.

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The course of infection due to Trypanosoma cruzi (Brazil strain) was examined in mutant and streptozotocin (STZ)-induced diabetic mice. Mutant diabetic mice (+db/+db) are obese, have elevated blood glucose levels, normal insulin levels and impaired cell mediated immunity (CMI). Their littermates

Endoplasmic reticulum in health and disease: the 12th International Calreticulin Workshop, Delphi, Greece.

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Starting from 1994, every 2 years, an international workshop is organized focused on calreticulin and other endoplasmic reticulum chaperones. In 2017, the workshop took place at Delphi Greece. Participants from North and South America, Europe, Asia and Australia presented their recent data and
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