cholic acid/ذرة

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Studies on the formation of cholic acid in subjects given standardized diet with butter or corn oil as dietary fat.

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Effect of type and amount of dietary fat and 1,2-dimethylhydrazine on biliary bile acids, fecal bile acids, and neutral sterols in rats.

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The effect of type (corn oil or lard) and quantity (5 or 20%) of dietary fat and 1,2-dimethylhydrazine (DMH) on the composition of biliary bile acids, fecal bile acids, and neutral sterols was studied in rats exposed to a given regimen for two generations prior to s.c. treatment with DMH for 20

Estimation of cholesterol and bile acid turnover in man by kinetic analysis.

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The kinetics of cholesterol and bile acid turnover were determined from an analysis of the biliary lipids after a single intravenous injection of labeled cholesterol. A compartmental model was designed for the system, and the fractional metabolic rates and fluxes were determined in one lean and two

Ethinylestradiol stimulates a biliary cholesterol-phospholipid cosecretion mechanism in the hamster.

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The mechanism of ethinylestradiol-induced biliary secretion of excess cholesterol, a potential causative factor of cholesterol gallstones, is not yet known. It might be related to altered bile acid metabolism, since the rate of cholesterol and phospholipid secreted into bile is thought to be

Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.

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OBJECTIVE Besides their role in lipid absorption, bile acids (BAs) can act as signalling molecules. Cholic acid was shown to counteract obesity and associated metabolic disorders in high-fat-diet (cHF)-fed mice while enhancing energy expenditure through induction of mitochondrial uncoupling protein

Reduced digestibility of beef tallow and cocoa butter affects bile acid excretion and reduces hepatic esterified cholesterol in rats.

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We investigated stearic acid (18:0) digestibility and how it affects bile acid excretion in male Sprague-Dawley rats fed diets containing (g 18:0/ 100 g fatty acids): pork lard (13); beef tallow (19); cocoa butter (35); corn oil (2) or corn oil plus cholestyramine for 25 d. Apparent lipid

The effect of dietary fat on bile salt synthesis in rat liver.

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The effect of dietary fat on conjugated cholic, chenodeoxycholic and tauro-beta-muricholic acid synthesis was studied using hepatocytes isolated from rats given a low-fat diet, or a low-fat diet mixed with 10% olive oil or 10% corn oil. The rats were totally biliary drained for 48 h prior to

Effects of dietary soybean globulins on plasma and liver lipids and on fecal excretion of neutral sterols in rats.

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Effects of low-fat (1% corn oil) diets containing an isonitrogenous level (3.2%) of either casein, soybean protein isolate or three soybean globulin fractions (total, 11S and 7S globulins) on plasma and liver lipids and on the excretion of fecal neutral sterols were examined in rats. When diets free

Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats.

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Hepatic cholesterol metabolism was studied in rats fed purified diets supplemented (9% wt/wt) with either fish oil (FO) (n-3 fatty acids) or corn oil (CO) (n-6 fatty acids) for 4 wk. Rats were equipped with permanent catheters in heart, bile duct, and duodenum to allow studies under normal feeding

Effect of bile acids and diet composition on lipid absorption in chickens with cannulated bile ducts.

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The effect of bile acids on lipid research was examined in meat-type chicks, 8 weeks of age, with cannulated cystic and hepatic ducts. The procedure allowed for biliary collection in free-roving birds. Shams retained 90 to 92% dietary fat and those with cannulated ducts retained 43 to 72%. Addition

Mechanism of trichloroethylene-induced elevation of individual serum bile acids. I. Correlation of trichloroethylene concentrations to bile acids in rat serum.

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The temporal relationship between trichloroethylene (TRI) and individual serum bile acids (SBA) has been investigated to gain insight into the mechanism of solvent-induced increases in SBA. Male Sprague-Dawley rats were treated with 1 mmol/kg TRI in corn oil, while control rats received only corn

Dietary fat and cholesterol modification of rat abdominal aorta prostacyclin and leukotriene production (in vitro).

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Groups of weanling male Sprague-Dawley rats fed formulated diets containing 15% by weight of corn oil (CO), linseed oil (LNO), or corn oil plus 1% cholesterol and 0.25% cholic acid (CH-CH) were sacrificed after 8 weeks and the aortas removed. Three mm length cross-sectional rings were cut from the

Hypocholesteremia induced by orotic acid: dietary effects and species specificity.

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Effects of 1% dietary orotic acid on lipid metabolism were examined in rats, mice, hamsters and guinea pigs. The influences of diet composition, age and sex on alterations induced by orotic acid were also studied. Hypocholesteremia and hepatic steatosis developed in rats fed orotic acid. These

Effect of geraniol, a plant derived monoterpene on lipids and lipid metabolizing enzymes in experimental hyperlipidemic hamsters.

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Hyperlipidemia is a major, modifiable risk factor for atherosclerosis and cardiovascular disease. In the present study, we have focused on the effect of different doses of geraniol (GOH) on the lipid profile and lipid metabolizing enzymes in atherogenic diet (AD) fed hamsters. Male Syrian hamsters

Dietary non-starch polysaccharides interact with cholesterol and fish oil in their effects on plasma lipids and hepatic lipoprotein receptor activity in rats.

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Male rats were fed the non-starch polysaccharides pectin, methylcellulose or guar gum with corn oil or with 60% of the corn oil replaced by fish oil. They were also fed these diets with or without cholesterol (+ cholic acid). Plasma total cholesterol concentration was higher overall in rats fed

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