BACKGROUND
Pancreatic cancer is one of the most devastating human cancers and is the fourth leading cause of overall cancer-related mortality in the United States. Currently, there is no clinically effective therapy for pancreatic cancer. The only chance for complete recovery is surgical resection;
BACKGROUND
Pancreatic cancer is one of the most devastating human cancers and is the fourth leading cause of overall cancer-related mortality in the United States. Currently, there is no clinically effective therapy for pancreatic cancer. The only chance for complete recovery is surgical resection;
BACKGROUND
Cancer is a leading cause of death in developed countries. Despite continuing advances in diagnosis and treatment regimens, most existing treatment methods have undesirable side effects and limited efficacy. Treatment of cancer is complicated by the variety of mechanisms involved in the
BACKGROUND
A variety of diseases involve the hyperproliferation of cells. Cancer, for example, is a commonly known hyperproliferative disease. Cancer is a large, heterogeneous class of diseases in which a group of cells display uncontrolled growth, resulting in an invasion that intrudes upon and
TECHNICAL FIELD
The present invention relates to novel coumarins, their carboxamide derivatives, the preparation method thereof and the pharmaceutical compositions containing them, and their use as medicaments for kidney protection, as well as for the treatment of hypertension,
CROSS-REFERENCE
This application claims priority under 35 U.S.C. .sctn.371 to Patent Cooperation Treaty application PCT/CN2013/084146, filed Sep. 25, 2013, which claims the benefit of Chinese patent application no. 201210363366.6, filed Sep. 27, 2012; Chinese patent application no. 201210363367.0,
This application is a 371 of PCT/JP94/00615 filed 12 Apr. 1994 and published as WO94/24119 Oct. 27, 1994.
TECHNICAL FIELD
The present invention relates to novel coumarin derivatives inhibiting 12-lipoxygenase selectively, and medicines containing these compounds as effective ingredients; and
CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a National Phase of and claims the benefit of PCT/IN2011/000515, with an international filing date of Aug. 5, 2011, which in turn claims priority to Indian Application No. 1843/DEL/2010, filed Aug. 5, 2010, the entire disclosures of
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase Application of PCT/CN2016/074796, filed Feb. 29, 2016, which claims priority to CN 201510618234.7, filed Sep. 24, 2015, the contents of which applications are incorporated herein by reference in their entirety for all
FIELD OF THE INVENTION
The invention relates to a novel class of compounds which have a structures related to naturally and synthetically occurring chalcones, as well as to methods for preparation of such compounds and to pharmaceutical uses thereof.
TECHNICAL FIELD
The compound
FIELD OF INVENTION
The present invention relates to medicaments for enhancing the effect of cancer therapy on the basis of mechanism of injuring DNA, and novel compounds useful as active ingredients of said medicament.
BACKGROUND ART
Anticancer agents are administered in treatments of cancer
FIELD OF THE INVENTION
The invention relates to a class of compounds which have a structure related to naturally and synthetically occurring flavanoids and to pharmaceutical uses of the compounds.
TECHNICAL FIELD
The development of multiple drug resistance represents an increasing problem in cancer
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology, chemistry, and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as cancer and other proliferative
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology, chemistry, and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as cancer and other proliferative
TECHNICAL FIELD
The present invention relates to a novel fluorescently labeled sugar derivative to which a specific coumarin derivative has been linked, and to a cell imaging method and an imaging agent using the same. Further, the present invention relates to a method for detecting and/or imaging
اكتب أحد الأعراض أو المرض واقرأ عن الأعشاب التي قد تساعد ، واكتب عشبًا واطلع على الأمراض والأعراض التي تستخدم ضدها. * تستند جميع المعلومات إلى البحوث العلمية المنشورة