craniofacial abnormalities/سمنة

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Craniofacial abnormalities, obesity, and hormonal alterations have similar effects in magnitude on the development of nocturnal hypoxemia in patients with acromegaly.

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BACKGROUND In patients with acromegaly, sleep apnea-related hypoxemia results in considerable morbidity and mortality. OBJECTIVE To evaluate the relative weight of pathogenic factors in predicting such hypoxemia. METHODS In this cross-sectional study, 34 acromegaly patients were submitted to

The relationship between obesity and craniofacial structure in obstructive sleep apnea.

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OBJECTIVE To evaluate the interaction between craniofacial structure and obesity in male patients with obstructive sleep apnea (OSA). METHODS Retrospective analysis of a cohort of OSA patients. The relationships between neck circumference (NC), body mass index, apnea severity, and craniofacial and

Craniofacial abnormalities in obstructive sleep apnoea: implications for treatment.

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Obstructive sleep apnoea (OSA) is a common disorder, and is characterized by repetitive closure of the upper airway during sleep. Upper airway narrowing and sleep-induced loss of muscle tone are important factors in the development of OSA. Over the last decade there has been a growing recognition

Craniofacial abnormalities in Japanese patients with severe obstructive sleep apnoea syndrome.

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OBJECTIVE To clarify that factors besides obesity play an important role in the development of obstructive sleep apnoea syndrome (OSAS) in Japanese patients, we compared craniofacial structures in patients with severe OSAS with those of normal controls. METHODS The craniofacial structures of 60

Facial patterns and primary nocturnal enuresis in children.

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OBJECTIVE Aims of our study are evaluating: (1) the prevalence of dolicofacial pattern among enuretic and control-group children, (2) the prevalence of an abnormal head posture in bedwetters, and (3) the correlation with sleep-related breathing disorders (SRBD) identified by polysomnography (PSG)

Prediction of obstructive sleep apnea using facial landmarks.

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The collapsibility of the upper airway has a known anatomical basis that is mediated by an interaction of obesity and craniofacial abnormalities. The pattern of these abnormalities, if detected in a subject's facial image, can help predict the presence of obstructive sleep apnea (OSA). OBJECTIVE We

Efficacy of powered intracapsular tonsillectomy and adenoidectomy.

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OBJECTIVE We sought to determine the effectiveness of powered intracapsular tonsillectomy and adenoidectomy (PITA) in the treatment of children with moderately severe obstructive sleep apnea and to measure changes in quality of life that occur with such treatment. METHODS Prospective, nonrandomized

A Comparison of Early Versus Late Prenatal Magnetic Resonance Imaging in the Diagnosis of Cleft Palate.

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Prenatal ultrasound is the standard modality to screen for fetal craniofacial malformations, but can be limited by sonographer experience, oligohydramnios, and maternal obesity. Fetal magnetic resonance imaging (MRI) can be used as an adjunct to ultrasound, but there is a paucity of

The pediatric use of bilevel positive airway pressure therapy for obstructive sleep apnea syndrome: a retrospective review with analysis of respiratory parameters.

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The purpose of this study was objective documentation of clinical benefits of bilevel positive airway pressure in pediatric patients with obstructive sleep apnea. We performed a retrospective chart review and data collection/analysis in a suburban tertiary care children's hospital. The study

Anatomical balance of the upper airway and obstructive sleep apnea.

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BACKGROUND Obesity and craniofacial abnormalities such as small maxilla and mandible are common features of patients with obstructive sleep apnea (OSA). The authors hypothesized that anatomical imbalance between the upper airway soft-tissue volume and the craniofacial size (rather than each alone)

Report on 3 patients with 12p duplication including GRIN2B.

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The duplication of the short arm (p) of chromosome 12 is a rare chromosomal abnormality, and most reported cases result from malsegregation of a balanced parental translocation associated with other chromosomal imbalances. Of the reported cases, only 15 involve a pure and complete 12p duplication

Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance.

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Contiguous gene syndromes (CGS) are a group of disorders associated with chromosomal rearrangements of which the phenotype is thought to result from altered copy numbers of physically linked dosage-sensitive genes. Smith-Magenis syndrome (SMS) is a CGS associated with a deletion within band p11.2 of

Rubinstein-Taybi Syndrome in a 19-years old boy.

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BACKGROUND Rubinstein-Taybi syndrome is a rare genetic multisystem disorder comprising motor organ dysfunction, craniofacial dysmorphism and psychomotor retardation, frequently with the abnormalities of the thyroid gland. OBJECTIVE Presentation of a case of a 19-year-old patient with

Peri-operative complications after adenotonsillectomy in a UK pediatric tertiary referral centre.

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OBJECTIVE Adenoidectomy and/or tonsillectomy are commonly performed in tertiary pediatric hospitals for the management of obstructive sleep apnea, often in children with significant comorbidities. This study examines the peri-operative course of a large series of complex patients undergoing such

Obstructive sleep apnea syndrome (OSAS): Pathophysiology in Estonians.

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The aim of the study was to clarify the roles of age, obesity, smoking, alcohol, pathoanatomy and -physiology in Estonian's OSAS. For this 164 randomly chosen such patients were selected in different regions of Estonia. They underwent naso-oropharyngeal examination, physical examination of

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