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The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance

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AIMS OF STUDY The aim of this study is to investigate whether ingestion of curcumin will prevent hepatic insulin resistance (assessed by homeostatic model assessment of insulin resistance (HOMA-IR)) induced by short-term oral glucocorticoid (prednisolone) administration in overweight and obese

7-day Atorvastatin and Emotional Processing

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Depression is common and associated with considerable health disability. Traditional antidepressants mainly work by modulating monoamine levels in the synaptic cleft; however, the evidence that depression is caused by impaired serotonin or noradrenaline activity is weak and inconsistent, and indeed

Prospective Cohort Study on Minimal Invasive Coronary Surgery

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1. MIDCAB procedure introduction 1. Surgery preparation: General anesthesia, double lumen tracheal intubation. In the supine position, tilt 15° to the right. An automatic defibrillation electrode is attached to the right front and left rear chest wall, and the external defibrillator is connected. A

Demographical and Clinical Profile of Patients on Dual Antıplatelet Therapy and Mean Precise-DAPT and DAPT Scores in Turkey

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Design The study is a national, multicenter, non-interventional, observational, prospective registry. Population Patients older than 18 years old of age, have acute coronary syndrome or percutaneous coronary intervention electively and with available admission hemoglobin, white blood cell and

Creatine Kinase Versus 3D Doppler for Antenatal Diagnosis of Abnormal Adherent Placenta.

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Abnormal placentation poses a diagnostic and treatment challenge for all providers caring for pregnant women. As one of the leading causes of postpartum hemorrhage, abnormal placentation involves the attachment of placental villi directly to the myometrium with potentially deeper invasion into the

Therapeutic Effect of Local Hypothermia in Treatment of Acute Myocardial Infarction

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Ethics and organization The study was designed in agreement with the Declaration of Nanjing, and the study protocol was approved by the local ethics committees. A written informed consent will be completed before inclusion. The trial was coordinated and monitored by the First Affiliated Hospital

Frailty In Cardiac Surgery Copenhagen Study

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Background: In general, patients referred to cardiac surgery are aging. An increasing number of patients are now older than 70 years. [1]This older population of patients undergoing cardiac surgery often has several comorbidities and has an increased risk of complications and mortality compared to

The Inter and Intra Reliability of Cardiopulmonary Exercise Testing in Abdominal Aortic Aneurysm Patients

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Background Research: The definition of an 'aneurysm' is permanent, localised dilatation of a blood vessel or heart chamber. The abdominal aorta is the largest blood vessel in the human body and usually has a diameter of 1.8 -2.0 centimetres (cm), dependant on age, sex and body habitus. Aortic

Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion

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PURPOSE Interactions between the hypothalamus-pituitary-adrenal axis, sympathetic nervous system and immunological system acts in the initiation and propagation to reactions of trauma distress. A large number of factors affect the activation of immune response owing to surgical trauma and

Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet Agents

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For patients who are found to have high-risk peptic ulcers on endoscopy, they will be treated by endoscopic combination therapy including adrenaline injection and followed by either thermal coagulation or haemoclips to achieve haemostasis. Peptic ulcers of high-risk stigmata are ulcers with active

Direct Anterior Approach Versus Direct Lateral Approach in Total Hip Arthroplasty

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This is a prospective randomised controlled clinical trial and follow-up study comparing primary total hip arthroplasty performed either through a direct anterior approach or a lateral approach. At our hospital(i.e. Emergency County Hospital Cluj-Napoca), the lateral transgluteal approach was

Rechargeable Neurostimulators in Deep Brain Stimulation for Psychiatric Disorders

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BACKGROUND Obsessive‐Compulsive Disorder [OCD] is a psychiatric disorder with a lifetime prevalence of 2% which is mainly characterized by obsessional ideas and compulsive behaviours and rituals. Many patients show improvement under cognitive behavioural and/or pharmacological treatment. A minority

StAtins for Venous Event Reduction in Patients With Venous Thromboembolism Pilot Study

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The SAVER pilot is a randomized, open-label pilot study to determine the feasibility of recruitment. In addition to feasibility data, the investigators will carefully collect clinical data to determine if rosuvastatin can reduce post-thrombotic syndrome (PTS) in venous thromboembolism (VTE)

STAT-STatin and Aspirin in Trauma

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This protocol describes a Phase II, pragmatic, prospective, randomized, double-blind, adaptive clinical trial comparing combination rosuvastatin and aspirin therapy to placebo. Currently, there is no treatment for fibrinolysis shutdown or effective measures to prevent macro- and micro-thrombosis

Takotsubo Cardiomyopathy in Patients Suffering From Acute Non-traumatic Subarachnoid Hemorrhage

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Data to be registered within 24 hours after admittance: - Age of the patient - Gender - Comorbidities - Currently taken medications - The exact time point of bleeding - Additional circumstances of the bleeding - Physical stress factors - Psychological stress factors - Significant blood pressure

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