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Involvement of MnSOD Ala16Val polymorphism in epilepsy: A relationship with seizure type, inflammation, and metabolic syndrome.

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The MnSOD Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to inflammatory pathways and many metabolic disorders, such as obesity and dyslipidemia. Metabolic syndrome (MetS) is an emergent problem among patients with epilepsy. However, little is known about interaction

Prevalence of post-stroke seizures in Srinagarind Hospital.

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OBJECTIVE Post-stroke seizures in Thailand have not been studied. Thus, the authors' main objective was to assess the prevalence of post-stroke seizures and the secondary objective was to determine the factors associated with post-stroke seizures and mortality after stroke. METHODS This was a

Hypertension on admission is associated with a lower risk of early seizures after stroke.

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OBJECTIVE Despite the common occurrence of early seizures (ES) after stroke, the relationship between risk factors and this complication of stroke is not well established. In this study we have examined the relationship between clinical measures on admission and ES after stroke. METHODS We included

Selective proximal renal tubular involvement and dyslipidemia in two cousins with oculocerebrorenal syndrome of Lowe.

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Oculocerebrorenal syndrome of Lowe (OCRL) is a rare, X-linked disorder characterized by congenital cataracts, neonatal or infantile hypotonia, seizures, cognitive impairment, and renal tubular dysfunction. In this article, we report two maternal cousins with OCRL with a hemizygous p.Ala788Asp

Natural course of neonatal progeroid syndrome.

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BACKGROUND Several progeroid disorders presenting a specific "old-man" appearance since birth or childhood have been described. Here, five patients with a history of severe intrauterine and postnatal growth retardation and pseudohydrocephaloid cranium noted after birth that were suggestive of

When Alice Took Sertraline: A Case of Sertraline-Induced Alice in Wonderland Syndrome

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Alice in Wonderland syndrome (AIWS) is a rare disorder that refers to episodic body image distortions, sometimes associated with altered perception of external space and time. AIWS is mainly associated with viral disease in children as well as migraines and epileptic seizures in adults. Its

Magnesium Supplementation did not affect the Antiseizure Property of Ketogenic Diet but Reduced Lipid Dysmetabolism.

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Ketogenic diets (KD) have been used globally in epilepsy management. Similarly, supplementation of diets with magnesium has been associated with disease prevention and improvement. However, the effect of magnesium (Mg) supplementation in conjunction with KD on epilepsy has not yet been

Importance of acylcarnitine profile analysis for disorders of lipid metabolism in adolescent patients with recurrent rhabdomyolysis: Report of two cases.

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Metabolic myopathies due to disorders of lipid metabolism are a heterogeneous group of diseases. Newborns may present with hypotonia and convulsions, while progressive proximal muscle weakness or recurrent episodes of muscle weakness accompanied by rhabdomyolysis/myoglobinuria may be seen in older

Recrudescence of Deficits After Stroke: Clinical and Imaging Phenotype, Triggers, and Risk Factors.

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UNASSIGNED Reemergence of previous stroke-related deficits (or poststroke recrudescence [PSR]) is an underrecognized and inadequately characterized phenomenon. UNASSIGNED To investigate the clinical features, triggers, and risk factors for PSR. UNASSIGNED This retrospective study incorporated a

[Spontaneous subarachnoid haemorrhage: a study of 462 patients].

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OBJECTIVE To describe the demographic characteristics of patients with spontaneous subarachnoid haemorrhage (SAH) in our population and to compare the endovascular and surgical treatment of intracranial aneurysms. METHODS We conducted a retrospective study of 462 patients who were admitted to the

Recurrent confusional episodes associated with hypomagnesaemia due to esomeprazol.

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In February 2011, the Food and Drug Administration informed that prescription of proton pump inhibitor (PPI) drugs may cause low serum magnesium levels if taken for prolonged periods of time. We present an ex-smoker, 76-year-old man, with high blood pressure, diabetes mellitus and Barrett's

Biochemical derangements related to metabolic syndrome in epileptic patients on treatment with valproic acid.

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OBJECTIVE Evaluation of biochemical derangements related to metabolic syndrome in epileptic patients on treatment with Valproic acid. METHODS This study consisted of two groups of 42 patients. Group I - Newly diagnosed patients with epileptic seizures untreated with any Anti-epileptic drugs (AEDs).

Impact of preoperative pasireotide therapy on invasive octreotide-resistant acromegaly.

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A 43-year-old woman with an 8-year history of diabetes, hypertension, and dyslipidemia presented with amenorrhea and convulsion. Her MRI scan revealed a 3.5-cm T2-hyperintense pituitary macroadenoma with suprasellar extension to the frontal lobe and bilateral cavernous sinus invasion. Her serum

Comparison of New-Onset and Persistent Epilepsy in the Elderly.

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BACKGROUND Previous studies on elderly epilepsy included only patients with new-onset disease, but there are many patients who developed epilepsy earlier and aged. OBJECTIVE We compared the characteristics of new-onset and persistence epilepsy in the elderly. METHODS We performed a 10-year

[The impact of demographic factors on the course and outcome of stroke].

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BACKGROUND The aim of the study was to answer the question, whether living in urban or suburban areas has an impact on disease course and outcome of stroke patients. METHODS The study included patients with a diagnosed cerebrovascular disease treated in the Department of Neurology, Provincial

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