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Ketoprofen: the European experience.

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An overview of European experience with ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties, from the time of its marketing in 1973 until the present is presented. Orally administered ketoprofen (200 mg/day) has been proven effective in treating rheumatoid arthritis,

European experience with flurbiprofen. A new analgesic/anti-inflammatory agent.

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Numerous European clinical trials begun more than 12 years ago have clearly demonstrated flurbiprofen's safety and efficacy as an analgesic, anti-inflammatory, and antipyretic agent. In preclinical studies, flurbiprofen was at least as potent as indomethacin, and approximately 200 times more potent

A European multicentre photopatch test study.

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BACKGROUND The two most common agent groups currently responsible for photoallergic contact dermatitis (PACD) are organic ultraviolet (UV) absorbers in sunscreens and topical nonsteroidal anti-inflammatory drugs (NSAIDs). However, availability of information on the photoallergenic potential of these

Diclofenac/misoprostol: the European clinical experience.

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OBJECTIVE The fixed combination of diclofenac sodium and misoprostol (Arthrotec) is the only nonsteroidal antiinflammatory drug (NSAID) that contains a gastroprotective component and is available in 2 formulations:(1) an enteric coated core of diclofenac sodium 50 mg surrounded by a mantle of

Equine recurrent uveitis: the European viewpoint.

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Equine recurrent uveitis (ERU) has always been and still is an important disease with a significant impact on the horse industry in Europe, with a prevalence of 8-10%. The need to understand and manage the disease has spurred the development of veterinary ophthalmology in general, although the

[European Resuscitation Council guidelines for resuscitation 2010].

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UNASSIGNED All rescuers trained or not, should provide chest compressions to victims of cardiac arrest. The aim should be to push to a depth of at least 5 cm at a rate of at least 100 compressions per minute, to allow full chest recoil, and to minimise interruptions in chest compressions. Trained

Nonsteroidal anti-inflammatory drugs and immunologic function. Overview of the European experience.

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A large number of nonsteroidal anti-inflammatory drugs are available in Europe. There appears to be little difference in overall clinical effectiveness of these drugs, despite individual patient variation, suggesting a common mode of action. Occasionally, a nonsteroidal anti-inflammatory drug will

Safety of thymopentin. Data from European clinical studies.

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The safety data collected from 196 patients treated with thymopentin during the clinical development of this compound in Europe are reviewed and compared with the incidence of adverse drug reactions experienced when using a commercial nonsteroid anti-inflammatory drug. Quantitatively side effects

The burden of arthritis and nonsteroidal anti-inflammatory treatment. A European literature review.

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The purpose of this literature review is to summarise data available from publications describing the burden of osteoarthritis and rheumatoid arthritis in Europe, and to highlight gaps in the literature. On the basis of extensive literature research, the epidemiology of arthritis, its treatment

European photopatch test baseline series: A 3-year experience.

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BACKGROUND In 2012, a consensus was reached regarding a baseline photopatch test series on the basis of the results of a European multicentre study. OBJECTIVE To describe experience with the European photopatch test series. METHODS A retrospective analysis of 116 patients tested with the European

European medicinal polypores--a modern view on traditional uses.

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BACKGROUND In particular five polypore species, i.e. Laetiporus sulphureus, Fomes fomentarius, Fomitopsis pinicola, Piptoporus betulinus, and Laricifomes officinalis, have been widely used in central European folk medicines for the treatment of various diseases, e.g. dysmenorrhoea, haemorrhoids,

Pain management in patients with haemophilia: a European survey.

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There are no evidence-based guidelines on pain management in people with haemophilia (PWH), who may suffer acute, disabling pain from haemarthroses and chronic arthropathic pain. To review evidence and to investigate current clinical practice in pain assessment and management in PWH the European

The psychopharmacology of European herbs with cognition-enhancing properties.

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Extensive research suggests that a number of plant-derived chemicals and traditional Oriental herbal remedies possess cognition-enhancing properties. Widely used current treatments for dementia include extracts of Ginkgo biloba and several alkaloidal, and therefore toxic, plant-derived cholinergic

The role of anti-inflammatory drugs in the treatment of osteoarthritis: a European viewpoint.

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Despite the fact that there is no scope for an inflammatory process in a strict definition of osteoarthritis (OA), inflammation nevertheless seems to be of great relevance in understanding not only the occurrence of the disease but also its propensity and/or persistence. Longitudinal epidemiologic

Anti-inflammatory steroidal glycosides from the berries of Solanum nigrum L. (European black nightshade).

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Seven previously undescribed steroidal glycosides, along with three known congeners were isolated from the unripe berries of Solanum nigrum L. (Solanaceae). Their structures were elucidated on basis of 1D and 2D NMR, HR-ESI-MS spectroscopic data and GC analysis after acid hydrolysis. The potential

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