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[Effects of cold, formaldehyde and anoxia on the lipids and glycogen in placentas of pregnant rats (Rattus norvegicus albinus, Rodentia, Mammalis)].

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Diverse electron sources support denitrification under hypoxia in the obligate methanotroph Methylomicrobium album strain BG8.

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Aerobic methane-oxidizing bacteria (MOB) are a diverse group of microorganisms that are ubiquitous in natural environments. Along with anaerobic MOB and archaea, aerobic methanotrophs are critical for attenuating emission of methane to the atmosphere. Clearly, nitrogen availability in the form of

Hypoxia-ischemia induces a rapid elevation of ubiquitin conjugate levels and ubiquitin immunoreactivity in the immature rat brain.

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Postnatal rats at 7 and 21 days of age were subjected to unilateral hypoxia-ischemia (H/I) by right carotid artery ligation followed by 1.5 to 2 hours of hypoxia (8% oxygen). Brains were frozen at specific intervals of recovery from 0 to 24 hours. Western blots of samples of right and left forebrain

Myocardial capillarity in acclimation to hypoxia.

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Capillarity, O2 diffusion distances and fiber cross-sectional growth were measured in the hearts of guinea pigs exposed early during growth to hypobaric hypoxia (PB = 430 torr, PO2 = 90 torr). Twelve 5-week old males were maintained in a hypobaric chamber for 4-14 weeks. Their hearts were

Intermittent hypobaric hypoxia during development--morphological and functional changes in the neocortex.

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Infant rats, together with their mother, were exposed to the simulated altitude of 7,000 m for 8 hours per day since birth to the age of 17 days. Animals were studied the 25th day, 8 days after the last exposure to hypoxia. The experimental and control animals were sacrificed the 25th day by the

[Intermittent hypobaric hypoxia during development--morphologic changes in the neocortex and hippocampus].

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Infant rats, together with their mother, were exposed to the simulated altitude of 7,000 m for 8 hours per day since birth to the age of 18 days. Animals were studied the 25th day, 7 days after the last exposure to hypoxia. The experimental and control animals were killed the 25th day by the

[The effect of benzine and formaldehyde on the prenatal development of rats with induced iron trace-element disorder].

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Iron-deficiency anemia induced in the maternal organism markedly enhances embryotoxic and teratogenic effects of the studied pollutants: gasoline and formaldehyde. The prenatal effects of these drugs against the background of iron-deficiency state in pregnant females leads to development of the main

Effect of magnesium pre-treatment on the hippocampal NOS activity during long-lasting intermittent hypoxia.

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Influence of magnesium pre-treatment during repetitive hypoxia was studied in the hippocampus of rats by histochemical analysis (NADPH-diaphorase staining). NADPH-diaphorase occurs concurrently with NO-synthase that is responsible for NO synthesis. Rat pups were kept together with their mother for 8

Effects of H2-receptor blockers on response of cerebral blood flow to normocapnic hypoxia.

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Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of

Influence of centrifugal sinus nerve activity on carotid body catecholamines: microphotometric analysis of formaldehyde-induced fluorescence.

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The effects of centrifugal activity in the carotid sinus nerve (CSN) on the intensity of formaldehyde-induced fluorescence of carotid body were examined in cat. Measurements of intensity were obtained from 21 to 56 sections of each carotid body with a microscope photometer attached to a fluorescence

Effects of unilateral hypoxia on neuroepithelial bodies in rabbit lungs.

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The present study was undertaken to investigate the influence of regional (unilateral) alveolar hypoxia on the intrapulmonary neuroepithelial bodies (NEB), which contain bioactive substances and are distinctly innervated. Eight (4-wk-old) rabbits were subjected to unilateral hypoxia. The animals

Effect of the inhibitor of nitric oxide synthase, NG-nitro-L-arginine methyl ester, on cerebral and myocardial blood flows during hypoxia in the awake dog.

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The increase in cerebral blood flow (CBF) elicited by moderate hypoxia in anesthetized animals is little attenuated by nitric oxide (NO) synthase inhibitors. However, in previous studies, the effects of NO synthase inhibitors may have been altered by anesthetics. Consequently, we studied the effects

Hypoxia-selective antitumor agents. 11. Chlorambucil N-oxide: a reappraisal of its synthesis, stability, and selective toxicity for hypoxic cells.

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The potential hypoxia-selective cytotoxin 4-[4'-[N,N-bis(2"-chloroethyl)amino]phenyl]butanoic acid N-oxide (chlorambucil N-oxide, 4) was synthesized and characterized as its hydrochloride salt. This compound was shown to be unstable, decomposing in some organic solvents to the hydroxylamine

Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia-ischemia injured mouse brains.

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OBJECTIVE We investigated whether oscillating gradient diffusion MRI (dMRI) can provide information on brain microstructural changes after formaldehyde fixation and after hypoxic-ischemic (HI) injury beyond that provided by conventional dMRI. METHODS Pulsed gradient spin echo (PGSE) and oscillating

Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features.

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In 55 Sprague-Dawley rats (mean wt, 277 +/- 6.2 g) exposed to hypobaric hypoxia (air at 380 mmHg), and 23 weight-matched controls kept in room air, pulmonary and systemic artery pressures were measured daily for 2 wk via indwelling catheters. After each day of exposure, 1 or 2 hypoxic rats, to a

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