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الصفحة 1 من عند 25 النتائج
Composition for prevention or treatment of cancer comprising N-methylenenaphtho[2,1-b]furan-2-carbohydrazide derivatives as an active ingredient
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a composition for the prevention and treatment of cell proliferative disease including cancer which comprises ethyl(2-methyl-3{(E)-[(naphtho[2,1-b]furan-2-ylcarbonyl)hydrazono]methyl}- -1H-indole-1-yl)acetate, the
Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
Lipid furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
Thiophene and furan 2,5-dicarboxamides useful in the treatment of cancer
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention relates to compounds that inhibit certain integrins, particularly to compounds that inhibit .alpha..sub.v integrins.
BACKGROUND OF THE INVENTION
Integrins are a major family of adhesion receptors. They are produced by most cell types and are a means by
2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
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FIELD OF THE INVENTION
The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in
Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer
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TECHNICAL FIELD
The present invention relates to novel water-soluble prodrugs of 2-acetylnaphtho[2,3-b]furan-4,9-dione, pharmaceutically acceptable salts thereof, or hydrates or solvates thereof useful as a medicament. The invention also relates to pharmaceutical compositions comprising a novel
2-aminothiazole derivative and anti-cancer composition comprising same as active ingredient
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CROSS-REFERENCE TO RELATED APPLICATION
This application is the U.S. national phase applications filed under 35 U.S.C..sctn.371 claims benefit to International Patent Application No. PCT/KR2012/008989, filed on Oct. 30, 2012, which is entitled to priority under 35 U.S.C .sctn.119(a)-(d) to Korea
Pyridine substituted furan derivatives as Raf kinase inhibitors
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
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This application is a .sctn.371 national stage filing of PCT/EP02/09944 filed 5 Sep. 2002.
This invention relates to novel compounds and their use as pharmaceuticals, particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine
Methods for treating cancer
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BACKGROUND
Disclosed herein are methods comprising administering to a subject a combination comprising a therapeutically effective amount of at least one compound chosen of formula (I) in combination with a therapeutically effective amount of at least one paclitaxel compound chosen from paclitaxel,
Certain tetrahydro-furan or pyran phosphate-ethylene or propylene ammonium derivatives
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
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BACKGROUND OF THE INVENTION
The present invention relates to a series of novel phosphate ester derivatives containing a cyclic ether system and provides processes for producing these compounds and compositions containing them for use as anti-cancer agents.
Many compounds have been shown to have
Telomerase inhibitors
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
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BACKGROUND OF THE INVENTION
1. The Field of the Invention
The present invention relates to human telomerase, a ribonucleoprotein enzyme involved in human telomere DNA synthesis, and to compounds that inhibit telomerase activity. The invention provides methods, compounds and compositions relating to
Processes for preparing 3-substituted 1-(chloromethyl)-1,2-dihydro-3H-[ring fused indol-5-yl-(amine-derived)] compounds and analogues thereof, and to products obtained therefrom
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
This application is the U.S. National Phase of International Application PCT/NZ03/00094, filed 19 May 2003, which designated the U.S. PCT/NZ03/00094 claims priority to New Zealand Application No. 519031 filed 17 May 2002. The entire content of these applications are incorporated herein by
Small molecule inhibitors of Mcl-1 and uses thereof
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FIELD OF THE INVENTION
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a [(1-piperazinyl)-4-pyridinylmethyl]-Naphtho[1,2-b]furan structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics
قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم
- يعمل في 55 لغة
- العلاجات العشبية مدعومة بالعلم
- التعرف على الأعشاب بالصورة
- خريطة GPS تفاعلية - ضع علامة على الأعشاب في الموقع (قريبًا)
- اقرأ المنشورات العلمية المتعلقة ببحثك
- البحث عن الأعشاب الطبية من آثارها
- نظّم اهتماماتك وابقَ على اطلاع دائم بأبحاث الأخبار والتجارب السريرية وبراءات الاختراع
اكتب أحد الأعراض أو المرض واقرأ عن الأعشاب التي قد تساعد ، واكتب عشبًا واطلع على الأمراض والأعراض التي تستخدم ضدها.
* تستند جميع المعلومات إلى البحوث العلمية المنشورة
