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Long-term clinical and seizure outcomes of insular gliomas via trans-opercular approach.

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OBJECTIVE To report long-term clinical and seizure outcomes of patients who were operated upon insular gliomas via trans-opercular approach. METHODS Since 2010, surgical resection of insular gliomas was performed via trans-opercular approach by our group. Clinical, surgical and follow-up results

Anti-leucine-rich Glioma-inactivated-1 Encephalitis with Faciobrachial Dystonic Seizures and Behavioral Problems: A Case Report

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Anti-Leucine-rich glioma-inactivated-1 encephalitis is a subtype of autoimmune encephalitis characterized by cognitive impairment, faciobrachial dystonic seizures, and behavioural changes. There is no reported case from Nepal. We report a case of a 54-year old male who presented with abnormal body

Risk factors for seizures and antiepileptic drug-associated adverse effects in high-grade glioma patients: A multicentre, retrospective study in Hong Kong.

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OBJECTIVE The aim of this present study was to determine the frequency, as well as risk factors, for seizures and antiepileptic drug (AED)-associated adverse effects among high-grade glioma (HGG) patients. METHODS A multicentre, retrospective study of adult Chinese Hong Kong patients from three

Predicting the likelihood of postoperative seizure status based on mRNA sequencing in low-grade gliomas.

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OBJECTIVE No comprehensive and objective methods yet exist for predicting postoperative seizure. METHODS mRNA-seq data and corresponding postoperative seizure status of 109 low-grade glioma samples were obtained from Chinese Glioma Genome Atlas database and divided into two sets randomly. Logistic

Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom.

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OBJECTIVE To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. METHODS A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). RESULTS Sixty five patients with were operated in

P450 enzyme-inducing and non-enzyme-inducing antiepileptic drugs for seizure prophylaxis after glioma resection surgery: a meta-analysis.

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OBJECTIVE The prognoses of seizure treatment with P450 enzyme-inducing and non-enzyme-inducing antiepileptic drugs after glioma resection surgery were investigated across several clinical studies. However, the results of these studies are inconsistent. We examined the relevant studies and conducted

Dysregulation of microRNA-128 expression in WHO grades 2 glioma is associated with glioma-associated epilepsy: Down-regulation of miR-128 induces glioma-associated seizure.

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Approximately 80% of glioma patients will experience at least one seizure activity during the course of the disease, and because the etiology of glioma-related seizure is most likely multifactorial and complex, it remains poorly understood. MicroRNAs are a class of small noncoding RNAs that function

Mutation analysis of the leucine-rich, glioma inactivated 1 gene (LGI1) in Japanese febrile seizure patients.

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Mutations in the leucine-rich, glioma inactivated 1 gene (LGI1) were recently identified in some families with autosomal dominant lateral temporal epilepsy (ADLTE). To investigate whether the LGI1 gene is a susceptibility gene for febrile seizures (FS), we performed a systematic search for mutations

[Diagnostic value of epileptic seizures in cerebral gliomas].

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On the basis of 346 glioma patients operated on in the years 1969-1983, the frequency of epileptic seizures and their importance for the diagnosis as well as the causes of the delay in clearing up the clinical picture were ascertained. Of the 226 patients with an astrocytoma, 51.5 per cent had one

Risk of seizures in children with tectal gliomas.

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The objective of this study was to determine the prevalence of seizures in children with tectal gliomas and to determine if there are common clinical, electroencephalography (EEG), or radiologic findings that predict risk of seizures in these patients. We conducted a retrospective review of all

Prophylactic diazepam in prevention of contrast media-associated seizures in glioma patients undergoing cerebral computed tomography.

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Five milligrams of intravenous diazepam given prior to contrast media injection statistically significantly reduced the incidence of contrast media-associated seizures from 16% to 2% in a prospective, randomized series of glioma patients. Factors related to increased risk of contrast

Perioperative seizure in patients with glioma is associated with longer hospitalization, higher readmission, and decreased overall survival.

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OBJECTIVE Seizures are among the most common perioperative complications in patients undergoing craniotomy for brain tumor resection and have been associated with increased disease progression and decreased survival. Little evidence exists regarding the relationship between postoperative seizures

An extent of resection threshold for seizure freedom in patients with low-grade gliomas.

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OBJECTIVE Seizures are the most common presenting symptom of newly diagnosed WHO Grade II gliomas (low-grade glioma [LGG]) and significantly impair quality of life. Although gross-total resection of LGG is associated with better seizure control, it remains unclear whether an extent of resection

[Clinical characteristics of epileptic seizures in insular gliomas].

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OBJECTIVE To study the characteristics of epileptic seizures in insular gliomas. METHODS Forty-five patients with insular gliomas were examined. The spread of a tumor was established by MRI results and intraoperational findings. A tumor within the insular only was found in 9 out of 45 patients (7

Pharmacotherapy of epileptic seizures in glioma patients: who, when, why and how long?

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BACKGROUND The risk for patients with primary brain tumors of experiencing an epileptic seizure at least once in the course of disease probably exceeds 50%, depending on tumor location and tumor type. Several aspects regarding the role of anticonvulsants in the treatment of brain tumor patients have

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Herbal & Natural Medicine

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