A 42-year-old male hemophiliac with micrognathia caused by temperomandibular hemarthrosis was studied for obstructive sleep apnea and successfully treated without the use of a tracheostomy. Prevention of nocturnal hypoxemia by nasopharyngeal intubation was found to relieve daytime hypersomnolence
The development of arthropathy is a major co-morbidity in patients with hemophilia. The present study was designed to study the role of a microRNA biomarker (miR-15b) in the development of joint disease. To investigate the expression profile of miR-15b during the development of arthropathy, we first
BACKGROUND
The present study was designed to investigate the molecular signaling events from onset of bleeding through the development of arthropathy in a murine model of hemophilia A.
RESULTS
A sharp-injury model of hemarthrosis was used. A global gene expression array on joint-specific RNA
Joint arthropathy secondary to recurrent hemarthroses remains a debilitating complication of hemophilia despite the use of prophylactic factor concentrates. Increased vascularity and neoangiogenesis have been implicated in the progression of musculoskeletal disorders and tumor growth. We
اكتب أحد الأعراض أو المرض واقرأ عن الأعشاب التي قد تساعد ، واكتب عشبًا واطلع على الأمراض والأعراض التي تستخدم ضدها. * تستند جميع المعلومات إلى البحوث العلمية المنشورة