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Lutein enhances survival and reduces neuronal damage in a mouse model of ischemic stroke.

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BACKGROUND Stroke is one of the leading causes of death worldwide. Protective agents that could diminish the injuries induced by cerebral ischemia/reperfusion (I/R) are crucial to alleviate the detrimental outcome of stroke. The aim of this study is to investigate the protective roles of lutein in

Association between higher plasma lutein, zeaxanthin, and vitamin C concentrations and longer telomere length: results of the Austrian Stroke Prevention Study.

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OBJECTIVE To examine the association between plasma concentrations of antioxidative micronutrients and leukocyte telomere length (LTL) in elderly adults. METHODS Cross-sectional cohort study. METHODS Austrian Stroke Prevention Study, a population-based cohort study on brain

Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers.

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OBJECTIVE Antioxidants may protect against atherosclerosis and thus prevent cerebrovascular disease. We studied the association between dietary antioxidants and subtypes of stroke. METHODS The study cohort consisted of 26 593 male smokers, aged 50 to 69 years, without a history of stroke. They were

Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States.

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BACKGROUND Antioxidants increase the resistance of low-density lipoprotein to oxidation and may thereby reduce risk for atherosclerosis. OBJECTIVE To determine whether intake of vitamin E, vitamin C, or carotenoids predict risk for total or ischemic stroke. METHODS Prospective observational

Effect of vitamin E, vitamin C, and beta-carotene on stroke risk.

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In a recent prospective observational study, vitamins C and E and beta-carotene did not elicit protective effects on stroke risk. Lutein, however, may elicit such protection. Nevertheless, these nutrients may be important modulators of the outcome after the occurrence of a stroke. At present,

Metastatic choriocarcinoma: a rare cause of stroke in the young adult.

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A 20-year old woman presented with acute right hemiplegia 10 weeks after intrauterine fetal death at 34-weeks gestation (G1P0). A brain MRI showed a typical acute infarct in the left middle cerebral artery territory. A CT pulmonary angiography carried out 1 week later for sudden cardiopulmonary

Effect of chlorella and its fractions on blood pressure, cerebral stroke lesions, and life-span in stroke-prone spontaneously hypertensive rats.

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Effects of Chlorella regularis (dried cell powder)--cultured axenically under heterotrophic conditions, and provided as a dietary supplement--and its fractions on the blood pressure, cerebral stroke lesions, and life-span of stroke-prone spontaneously hypertensive rats (SHRSP/Izm) were investigated.

The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis.

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BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress, but evidence has not systematically been evaluated. OBJECTIVE We aimed to evaluate systematically the effects of lutein (intake or concentrations)

Prospective study of plasma carotenoids and tocopherols in relation to risk of ischemic stroke.

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OBJECTIVE Intake of fruits and vegetables has been related to lower risk of ischemic stroke, but nutrients responsible for this apparent benefit remain ill-defined. Tocopherols (vitamin E) have also been proposed to be protective. METHODS We conducted a prospective, nested case-control analysis

Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review.

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Stroke and other cerebrovascular diseases are among the most common causes of death worldwide. Prevention of modifiable risk factors is a cost-effective approach to decrease the risk of stroke. Oxidative stress is regarded as the major flexible operative agent in ischemic brain damage. This review

Lutein and zeaxanthin and their potential roles in disease prevention.

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Lutein and zeaxanthin are xanthophyll carotenoids found particularly in dark-green leafy vegetables and in egg yolks. They are widely distributed in tissues and are the principal carotenoids in the eye lens and macular region of the retina. Epidemiologic studies indicating an inverse relationship

Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: relationship to early outcome.

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An association between ischemic stroke and increased oxidative stress has been suggested from animal studies. However, there is a lack of evidence with respect to this association in humans. Here, the time course of plasma levels of six carotenoids, which are lipophilic micronutrients with

Effect of long-chain ω-3 fatty acids and lutein + zeaxanthin supplements on cardiovascular outcomes: results of the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.

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OBJECTIVE Dietary supplements have been proposed as a mechanism to improve health and prevent disease. OBJECTIVE To determine if supplementing diet with long-chain ω-3 polyunsaturated fatty acids or with macular xanthophylls results in a reduced rate of cardiovascular disease (CVD). METHODS The

Plasma antioxidants and cognitive performance in middle-aged and older adults: results of the Austrian Stroke Prevention Study.

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OBJECTIVE To study the association between cognitive status and plasma concentrations of various antioxidants in middle-aged and older individuals without neuropsychiatric disease. METHODS Evaluation of cross-sectional data from a cohort study. METHODS The Austrian Stroke Prevention Study. METHODS A

Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men.

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BACKGROUND Emerging evidence suggests a possible role of lycopene in the primary prevention of cardiovascular disease (CVD). OBJECTIVE We examined whether plasma lycopene concentrations in the Physicians' Health Study were associated with CVD in a prospective, nested, case-control

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