Control will be 109 g white bread and 200 mL water. The glycaemic response to the test meal will be compared to the response of the control meal.

Test will be 109 g white bread and 200 mL water containing 3.819 g citric acid and 119 mg malic acid adjusted to pH 3.2. The glycaemic response to this meal will be compared to that of the control meal.

Hyperglycemia, Postprandial

Control will be 109 g white bread to be consumed together with 200 mL water

Control

Test will be 109 g white bread to be consumed together with 3.819 g citric acid and 119 mg malic acid dissolved in 200 mL water adjusted to pH 3.2.

Test

School of Food Science and Nutrition, University of Leeds

The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response to White Bread.

The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response

The incremental area under the glucose curve after consumption of the test meal will be compared to that obtained after the control meal

Gary Williamson

Prof functional foods

University of Leeds

Inflammation

Flavonoid

Placebo

Appalachian State University Human Performance Lab, North Carolina Research Campus

Flavonoid-rich Supplement Influence on the Human Metabolome

Influence of Ingesting a Flavonoid-rich Supplement on the Human Metabolome and Concentration of Urine Phenolics

24-h urine samples collected pre-study and after 12-weeks intervention

Blood sample analysis for shifts in metabolites pre-study and after 12-weeks intervention

A 4-week retrospective symptom log will be administered pre-study, 4-weeks, 8-weeks, and 12-weeks to document potential adverse gastrointestinal and mental effects.

Comprehensive blood diagnostic chemistry panels

Data will be shared through the Human Metabolome Database (HMDB), other public web sites, and publication in the scientific literature.

malic acid/سمنة

The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response to White Bread.

Flavonoid-rich Supplement Influence on the Human Metabolome

قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم