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Monosaccharide transport by the small intestine of lean and genetically obese (ob/ob) mice.

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The effect of the obese (ob/ob) genotype on monosaccharide transport in mouse small intestine has been examined, using several different methodologies, at various stages in the development of the syndrome. Evidence for an elevation of the total capacity of the small intestine for monosaccharide

L-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice.

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L-Fucose (Fuc), a six-deoxy hexose monosaccharide, is present endogenously in humans and animals and has a wide range of biological functions. In the present study, we aimed to examine the effect of Fuc on obesity and hepatic steatosis in mice fed a high-fat diet

[Epidemiological problems of obesity].

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The results of epidemiological survey of the population living in the middle zone of the Soviet Union and in the GDR are considered. Comparison of the data obtained shows that overweight is a very prevalent abnormal condition among the test population groups in both countries and amounts to 26%

[Postprandial thermogenesis and obesity: effects of glucose and fructose].

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In order to check whether reduced postprandial thermogenesis, as found in obese subjects depends on insulin resistance, the study tested whether the thermogenetic response to glucose in a group of obese subjects and a group of normal weight subjects differed from that obtained using an

The non-enzymatic glycation of LDL proteins results in biochemical alterations - A correlation study of Apo B100-AGE with obesity and rheumatoid arthritis.

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Advanced glycation end-products (AGEs) can aggregate amid incessant inflammation, as may be available in patients with rheumatoid arthritis. d-Ribose reacts more promptly than glucose monosaccharide to the proteins and forms heterogeneous group of products known as AGEs. Obesity includes persons

The anorectic effect of increasing doses of L-tryptophan in obese patients.

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Serotonin (5-HT) synthesis in neurons is initiated by hydroxylation of the essential amino acid tryptophan. Treatments that raise the level of tryptophan in the brain can rapidly alter the rate at which it is converted to 5-HT. This paper compares the effect of 1, 2 and 3 g L-tryptophan administered

Comparison of Anti-Obesity Effect between Two Types of Syrup Containing Rare Sugars in Wistar Rats.

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D-Allulose-containing rare sugar sweeteners have been categorized into two types, rare sugar syrup (RSS), consisting of 4 rare monosaccharides, and modified glucose syrup (MGS), rich in D-allulose, which was previously referred to D-psicose. The anti-obesity effect of RSS and D-allulose has been

Antioxidation, hepatic- and renal-protection of water-extractable polysaccharides by Dictyophora indusiata on obese mice.

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The present work aimed to investigate the antioxidation, hepatic- and renal-protection of water-extractable polysaccharides (WPS) by Dictyophora indusiata fruiting body on high-fat emulsion-induced obese mice. The structural analysis indicated that WPS was the α-configurational heteropolysaccharide

Phentermine/topiramate for weight reduction and treatment of adverse metabolic consequences in obesity.

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Phentermine hydrochloride is a noradrenergic sympathetic amine approved for decades by the U.S. Food and Drug Administration (FDA) at doses as high as 37.5 mg/day for the short-term treatment of obesity. Topiramate is a sulfamate-substituted monosaccharide marketed since 1996, and approved by the

Metabolic Abnormalities in Normal Weight Children Are Associated with Increased Visceral Fat Accumulation, Elevated Plasma Endotoxin Levels and a Higher Monosaccharide Intake.

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Being overweight has been identified as the main risk factor for the development of metabolic disorders in adults and children. However, recent studies suggest that normal weight individuals are also frequently affected by metabolic abnormalities with underlying mechanisms not yet fully understood.

Fructose levels are elevated in women with polycystic ovary syndrome with obesity and hyperinsulinemia.

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Are fructose levels altered in women with polycystic ovary syndrome (PCOS)?Elevated serum fructose levels are associated with PCOS in Chinese Han women with overweight/obesity and hyperinsulinemia, and fructose levels are higher in follicular fluids from

Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents.

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Increased sugar-sweetened beverage consumption has been linked to higher rates of obesity. Using functional MRI, we assessed brain perfusion responses to drinking two commonly consumed monosaccharides, glucose and fructose, in obese and lean adolescents. Marked differences were observed. In response

Metabolomic analysis of livers and serum from high-fat diet induced obese mice.

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Liver and serum metabolites of obese and lean mice fed on high fat or normal diets were analyzed using ultraperformance liquid chromatography-quadrupole-time-of-flight mass spectrometry, gas chromatography-mass spectrometry, and partial least-squares-discriminant analysis (PLS-DA). Obese and lean

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene.

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The liver produces plasma sex hormone-binding globulin (SHBG), which transports sex steroids and regulates their access to tissues. In overweight children and adults, low plasma SHBG levels are a biomarker of the metabolic syndrome and its associated pathologies. Here, we showed in transgenic mice

Maternal adiposity alters the human milk metabolome: associations between nonglucose monosaccharides and infant adiposity

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Background: Human milk composition is altered by maternal obesity. The association between milk metabolites and infant outcomes has not been thoroughly investigated. Objectives:

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