multiple myeloma/صداع

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Headache--a rare presenting symptom in multiple myeloma: a case report.

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Headache is a rare symptom in multiple myeloma (MM). A 34-year-old black female presented with severe headache and investigation subsequently led to the diagnosis of non-secretory MM. Non-secretory MM is seen in less than one percent of MM cases. Further-more, less than two percent of MM cases are

Reversible posterior leucoencephalopathy syndrome associated with bortezomib in a patient with relapsed multiple myeloma.

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Reversible posterior leucoencephalopathy syndrome (RPLS) is a potentially fatal but reversible clinico-radiological syndrome with symptoms of headache, altered mental functioning, visual changes and seizures in association with typical posterior cerebral white matter lesions. RPLS is associated with

Thalidomide for the treatment of refractory multiple myeloma: association of plasma concentrations of thalidomide and angiogenic growth factors with clinical outcome.

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Recent reports showed that thalidomide has anti-angiogenic activity and is effective for the treatment of refractory multiple myeloma (MM). We examined the relationship between the clinical efficacy and adverse effects of thalidomide and the plasma concentrations of this drug as well as angiogenic

Multiple Myeloma with intracranial plasmacytoma.

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We present a case of a 43-year-old male who was found to have an intracranial mass lesion on headache imaging. On further follow up, the patient developed systemic features of hypercalcemia, anemia and renal dysfunction. The biopsy of the mass was negative multiple times. A bone marrow biopsy was

[Multiple myeloma as a treatable cause of stroke: clinical case and review of the literature].

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Monoclonal and polyclonal immunoglobulinemia, including lymphoma, Waldenström's macroglobulinemia and less commonly multiple myeloma (MM), are considered as infrequent causes of ischemic stroke. Hyperviscosity states, as well as procoagulant disturbances, both potentially treatable, have been

Otogenic pneumocephalus as a complication of multiple myeloma.

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We report a case of otogenic pneumocephalus in an 80-year-old woman with multiple myeloma. The pneumocephalus was associated with Haemophilus influenzae otitis media and reactive meningitis in the absence of an intracranial brain abscess. Myeloma causes thinning of bone trabeculae and destructive

[Multiple myeloma. Diagnostic errors].

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Multiple myeloma is a disease with slow incidence and polymorphous signs and symptoms. We need don't overlook the unspecific symptoms like headache or bone pain.

Diplopia as the initial symptom of multiple myeloma in a patient with sarcoidosis

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We present the case of a 45-year-old man with a known history of sarcoidosis who presented with double vision and headache. On examination, he was found to have left abducens and hypoglossal nerve palsy. CT and then MRI demonstrated extensive osseous lesions with a large expansile mass involving the

[One Case of Multiple Myeloma with Central Never System Infiltration].

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OBJECTIVE To analyses and summarize a case of multiple myeloma with disseminated infiltration in central nervous system. METHODS The results of laboratorial examination and clinical data were analyzed and compared in the light of published literatures. RESULTS The headache and diplopia were caused

Multiple myeloma manifesting as an intraventricular brain tumor.

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Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing

Sellar solitary plasmacytoma progressing to multiple myeloma: a case report and literature review.

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Sellar plasmacytoma is a rare cause of sellar lesions. Preoperative diagnosis remains a challenge. We present a 34-year-old Chinese woman with a 25-day history of headache and diplopia. A physical examination revealed incomplete left abducens nerve palsy. The initial diagnosis was invasive pituitary

Extrapyramidal Symptoms with Administration of Lenalidomide Maintenance Therapy for Multiple Myeloma.

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Lenalidomide is commonly used as induction or maintenance therapy in multiple myeloma. We report a case of 71-year-old female presenting with tardive dyskinesia-like symptoms one month after starting her lenalidomide maintenance therapy after high-dose chemotherapy and autologous hematopoietic stem

[First case described of isolated, complete and fluctuating cranial nerve III palsy heralding multiple myeloma].

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BACKGROUND Multiple myeloma is the most common plasma-cell malignancy. To be incurable, treatment aims to obtain the longest non-clinical survival time. Cranial nerve palsy in multiple myeloma is extremely rare and is usually due to an intracranial plasmacytoma. We present a multiple myeloma case,

[A case of multiple myeloma showing intracranial hypertension due to large cranial mass lesions].

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It is well known that the case of multiple myeloma shows punched-out lesions of the cranium without intracranial hypertension. In this paper a case of multiple myeloma is reported showing intracranial hypertension due to a large tumor that developed in the left parietal bone. There are only 13 case

[Systemic varicella-zoster infection during ixazomib-containing multiagent chemotherapy for multiple myeloma]

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A 58-year-old man received high-dose melphalan with autologous peripheral blood stem cell transplantation for multiple myeloma in stringent complete response (sCR). Relapse occurred 4 years after the transplantation, and he was placed on ixazomib, lenalidomide, and dexamethasone (IRd) and achieved

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