niacin/صداع

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Sustained-release niacin for prevention of migraine headache.

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Considerable advances in the diagnosis and treatment of migraine headache have occurred during the past decade, but treatment options for acute migraine attacks have expanded at a faster rate than those for prophylaxis. We describe a patient whose migraine headaches responded dramatically to

The treatment of migraines and tension-type headaches with intravenous and oral niacin (nicotinic acid): systematic review of the literature.

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BACKGROUND Migraine and tension-type headaches impose a tremendous economic drain upon the healthcare system. Intravenous and oral niacin has been employed in the treatment of acute and chronic migraine and tension-type headaches, but its use has not become part of contemporary medicine, nor have

Clinical study of headache relief with a niacin-containing compound.

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Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions.

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OBJECTIVE To compare the effects of pretreatment with two aspirin regimens and placebo on niacin-induced cutaneous reactions. METHODS Randomized, double-blind, placebo-controlled, crossover study. METHODS Internal medicine clinic in an academic health center. METHODS Forty-two healthy subjects (22

Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia.

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Combination therapy is increasingly recommended for patients with multiple lipid disorders, especially those at high risk for coronary events. We investigated the long-term safety and effectiveness of a new drug formulation containing once-daily extended-release niacin and lovastatin. A total of 814

Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study

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Objective: The aim of the present research is to evaluate and to compare various nutraceuticals and food supplements in the headaches prophylaxis. Background: Recently the use

An open-label, crossover study of the pharmacokinetics of Insoluble Drug Delivery-MicroParticle fenofibrate in combination with atorvastatin, simvastatin, and extended-release niacin in healthy volunteers.

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BACKGROUND Fenofibrate has been prescribed concomitantly with other lipid-lowering agents as a treatment for dyslipidemia. However, combination therapy, particularly a statin-fibrate combination, may be associated with an increased risk of myopathy, although this risk appears to be less with

Niacin treatment of hypercholesterolemia in children.

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OBJECTIVE To determine the efficacy and adverse effects of niacin treatment of hypercholesterolemia in children. METHODS Retrospective review. METHODS Two university hospital referral clinics. METHODS All children who received single-drug niacin treatment for severe hypercholesterolemia between 1980

A single-dose, 3-way crossover pharmacokinetic comparison between immediate-release oxycodone hydrochloride with aversion technology (IRO-A, Oxecta), IRO-a with Niacin, and Oxycodone Hydrochloride (Roxicodone) in healthy adults under fasting conditions.

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Snorting and intravenous use are common routes of administration for advanced opioid abusers. A tablet form of immediate-release oxycodone (IRO) developed using Aversion Technology combines immediate release (IR) oxycodone HCl with inactive functional excipients that are intended to discourage

Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications.

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Niacin (also known as "vitamin B₃" or "vitamin PP") includes two vitamers (nicotinic acid and nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). The two coenzymes are required for

The role of nutrients in the pathogenesis and treatment of migraine headaches: Review.

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OBJECTIVE Migraine as a disabling neurovascular disease affects 6% of men and 18% of women worldwide. The deficiency of many nutrients including magnesium, niacin, riboflavin, cobalamin, coenzymes Q10, carnitine, α-lipoic acid and vitamin D is associated with migraine. Some researchers postulate

Clinical implications of the biopharmaceutical properties of fluvastatin.

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Fluvastatin sodium (Lescol; Sandoz) the first entirely synthetic 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor studied, is structurally distinct from the other HMG-CoA reductase inhibitors currently available, all of which are fungal metabolites and analogues of compactin.

Recognition and Differential Diagnosis of Psychosis in Primary Care.

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Psychosis is a symptom complex that may include hallucinations, delusions, disorders of thought, and disorganized speech or behavior. Acute psychosis is primary if it is symptomatic of a psychiatric disorder, or secondary if caused by a specific medical condition. Patients with primary psychiatric

A multicenter study of nutraceutical drinks for cholesterol (evaluating effectiveness and tolerability).

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BACKGROUND We hypothesized that a nutraceutical formulation containing small amounts of bioactive constituents that exert cholesterol-lowering effects by different mechanisms may exhibit synergistic efficacy with a clean tolerability profile. The purpose of this study was to evaluate nutraceutical

Mitochondrial dysfunction in migraine.

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Migraine is the most frequent type of headache in children. In the 1980s, scientists first hypothesized a connection between migraine and mitochondrial (mt) disorders. More recent studies have suggested that at least some subtypes of migraine may be related to a mt defect. Different types of

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