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Case 8-2019: A 58-Year-Old Woman with Vision Loss, Headaches, and Oral Ulcers.

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Early neurosyphilis presenting with facial palsy and an oral ulcer in a patient who is human immunodeficiency virus positive: a case report.

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BACKGROUND Neurosyphilis is the tertiary stage of Treponema pallidum infection that involves the central nervous system, which occurs within days or weeks after an initial syphilis infection, especially in immunocompromised patients. The diagnosis of neurosyphilis is quite challenging as it is

Apremilast to treat oral ulcers in Behçet syndrome.

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Apremilast, an oral small molecule, is a phosphodiesterase 4 (PDE-4) blocker. It has been shown to be efficacious in managing psoriasis (PS) and psoriatic arthritis (PSA). In two controlled studies, it was also effective in controlling oral ulcers of Behçet syndrome (Bsy). The main side effects

Trial of Apremilast for Oral Ulcers in Behçet's Syndrome.

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The small-molecule phosphodiesterase 4 inhibitor apremilast modulates cytokines that are up-regulated in Behçet's syndrome. In a phase 2 trial involving patients with Behçet's syndrome, apremilast reduced the incidence and severity of oral ulcers. Data on the efficacy and safety of

Behcet's disease presenting with cerebral vasculitis: a case report.

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BACKGROUND Behcet's disease encompasses a group of multisystemic complications secondary to occlusive vasculitis. It presents usually with oral or genital ulcers however, other system involvements may be the first sign as well. METHODS A 26-years-old man admitted to our clinic for his decreased

Neuro-Behçet's Disease Presenting as Hypertrophic Pachymeningitis.

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A 25-year-old man presented with blurred vision and chronic headache. His brain MRI revealed bilateral frontal pachymeningeal enhancement with leptomeningeal enhancement. The patient had experienced recurrent oral ulcer and had anterior uveitis and papulopustules skin lesion. We diagnosed him with

The safety and tolerance of atovaquone/proguanil for the long-term prophylaxis of plasmodium falciparum malaria in non-immune travelers and expatriates [corrected].

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BACKGROUND In Europe, atovaquone/proguanil (A/P) is only licensed for malaria prophylaxis for 28 days of travel. Data on the long-term safety and tolerance in nonimmune travelers are scarce. METHODS We initiated a prospective observational study on ailments reported by travelers using A/P on a

Longitudinal Myelitis of a Neuro-Behçet Patient.

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Behçet's disease is a chronic, relapsing inflammatory disorder of unknown etiology. Neuro-Behçet's disease (NBD) occurs in approximately 5 to 49% of patients with Behçet's disease. Spinal cord involvement is very rare in NBD. In this article, we report a 22-year-old male patient of NBD with

Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.

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Biolimus A9 (BA9) is a novel proliferation inhibitor of coronary smooth muscle cells that has been specifically designed for coating drug-eluting stents. The goals of this study were to identify the highest safe intravenous dose of BA9, to evaluate the dose-dependent pharmacokinetics of BA9 after

A case of central nervous system lupus associated with ruptured cerebral berry aneurysm.

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At the age of 29, a woman developed central nervous system manifestations of incontinence, psychosis and a grand mal seizure in February 1982. She was diagnosed as having systemic lupus erythematosus (SLE) based on photosensitivity, oral ulcers and elevated antinuclear and anti-DNA antibodies

[Orbital inflammatory pseudotumor with optic neuritis in Behçet's disease].

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OBJECTIVE To report an atypical case of orbital inflammatory pseudotumor associated with optic neuritis revealing Behçet's disease. METHODS A 37-year-old man was worked up for headache and progressive decreased bilateral visual acuity most profound in the left eye. Initial ophthalmologic exam was

Papilledema in Behçet's syndrome.

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Six patients with Behçet's syndrome (five male, one female) had intracranial hypertension diagnosed by elevated CSF pressure in the presence of normal or small ventricles. All six patients had headaches and papilledema. Histories included oral ulcers in 5 patients, genital ulcers in 3, uveitis in 1,

Clinical observations and virological study of aseptic meningitis in the Kaohsiung area.

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During 1988, an endemic outbreak of aseptic meningitis was noted in the Kaohsiung area. Throughout the year, a total of 89 cases were identified by cerebrospinal fluid (CSF) examination at the Pediatric Department of Kaohsiung Medical College. The peak incidence was from June to October. Scattered

Lupus-specific autoantibodies in concomitant human immunodeficiency virus and systemic lupus erythematosus: case report and literature review.

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OBJECTIVE To report a case of systemic lupus erythematosus (SLE) in a patient with human immunodeficiency virus (HIV) infection. We also reviewed the medical literature for similar cases to assess the role of "lupus-specific antibodies" in the diagnosis of SLE in the presence of HIV

[Behçet disease in children in France].

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BACKGROUND Behçet's disease is rare in children. The possibility of incomplete forms and the fact that the criteria for its diagnosis are not still agreed upon may explain why it could occur more frequently. METHODS A questionnaire was sent to all 362 French pediatric units. It requested data on

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