Patients with a history of Cluster Headaches and other TACs, or Trigeminal Neuralgia.

Healthy volunteer controls and family members may be enrolled for identification of genetic mutations.

Cluster Headache

Cluster Headaches and Other Trigeminal Autonomic Cephalgias

Paroxysmal Hemicrania

SUNCT

Hemicrania Continua

Trigeminal Neuralgia

The University of Texas Health Science Center at Houston

The Will Erwin Headache Research Center - Cluster Headache Study

The Will Erwin Headache Research Center Study of Cluster Headache and Trigeminal Neuralgia

Results of ELISAs for autonomic, hypothalamic, and pain signalling molecules

Mark J Burish

Assistant Professor, Neurosurgery

The University of Texas Health Science Center, Houston

Refractory Chronic Headache Disorders

Département d'Evaluation et Traitement de la Douleur

French Database of Occipital Nerves Stimulation in the Treatment of Refractory Chronic Headache Disorders

ocial and demographic data, medical data (headache features, headache functional and emotional impact, medications, and concomitant medical conditions), technical data (kind of electrodes and implantable pulse generator used, stimulation parameters chosen), and safety data.

Centre Hospitalier Universitaire de Nice

Stimulation frequency and pulse width will be uniformly held constant at 60 Hz and pulse width at 450 ms. The perception and discomfort amplitude will be defined by increasing the stimulation amplitude in steps of 0.1 V. The amplitude at which the patient starts feeling paraesthesis is called the perception threshold. The threshold at which the patient does not want the voltage to be increased any further because of painful sensations is designated the discomfort threshold. 100% stimulation is defined as stimulation at 90% of the range between perception and discomfort thresholds.

30% stimulation means a stimulation level at 30% of the range between perception threshold and 100% stimulation level

Chronic Cluster Headache

Low occipital bilateral Quad Plus, midline to laterally directed, secured by titan anchors, connected to Versitrel. No trial stimulation. Suggested stimulation parameters: Pulse width: 450, Amplitude: protocol, Rate: 60

occipital nerve stimulation

CHR La Citadelle hospital

Schmerzklinik Kiel

National Institute of Neuroscience

Boerhaave MC

Atrium medical centre

Leiden University Medical Center

Canisius Wilhelmina Hospital

Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache

An attack is defined as any attack recognised by the patient as being a CH attack. So also the attacks treated with oxygen or triptans.

The investigators will ask the patient whether he/she would recommend the treatment to another patient using a 5 point (Likert) scale: Strongly disagree, disagree, neither agree nor disagree, agree, strongly agree.

It is also investigated whether predictive factors can be identified with respect to the outcome in a hypothesis generating manner. We will look at the body mass index (BMI) and assess the predictive value of response after 5-7 days.

All and treatment-related adverse events will be documented by the investigators.

MAF: We will repeat the primary analysis, with the MAF as outcome instead of the logarithm of the MAF.

paroxysmal hemicrania/صداع

The Will Erwin Headache Research Center - Cluster Headache Study

French Database of Occipital Nerves Stimulation in the Treatment of Refractory Chronic Headache Disorders

Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache

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