الصفحة 1 من عند 264 النتائج
Nitrite-induced transformation of 3-amino-4-monomethylamino-2',7'-difluorofluorecein (DAF-FM) to the triazol form (DAF-FMT) was studied using bacterial fraction of mixed whole saliva. The transformation at pH 7 was inhibited by SCN(-), suggesting that nitrosative stresses were small in the oral
Introduction. Plant extracts may be suitable alternative treatments for caries. Aims. To investigate the in vitro and in vivo antimicrobial effects of Plantago lanceolata herbal tea (from flowers and leaves) on cariogenic bacteria and to identify the major constituents of P. lanceolata plant.
Scorpion envenomation has been considered a public health issue around the world. Tityus serrulatus represents a specie of major medical importance in Brazil due to mortality rates of approximately 1% among children and elderly populations. The aim of this work was to evaluate the in vivo
Phenolic acids have been extensively studied because of their bioactive properties and disease prevention and control capacities. However, undesired odors and taste, low aqueous solubility, and thermal and ultraviolet (UV) light instability severely restrict their application. The aim of this work
Phenolic compounds are widely used in clinical dentistry as sedatives for the dental pulp, as disinfectants for caries, and as root canal medications. The pathobiological effects of various phenolic compounds on human dental pulp fibroblasts were investigated with Hoechst 33258 fluorescence assay
Natural and synthetic phenolic compounds were evaluated against oral bacteria. A quantitative structure-active relationship approach was applied to the germ-kill activity for a range of phenolic compounds. The lipophilicity and steric effects were found to be two key factors in determining germ-kill
A series of phenolic acid esters incorporating caffeic, ferulic, and p-coumaric acid, and benzyl, m/p-hydroxyphenethyl- as well as p-hydroxy-phenethoxy-phenethyl moieties were investigated for their inhibitory effects against the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). Many of the
A series of phenolic acids and phenol natural products, such as p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, ferulic acid, gallic acid, syringic acid, quercetin, and ellagic acid, were investigated for their inhibitory effects against the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1).
Prenylated phenolic compounds are an important class of bioactive natural products. One major in vivo metabolic pathway of these compounds is hydroxylation at terminal methyl of the isoprenyl group. This study aims to identify the P450 isozyme catalyzing this metabolic reaction. In human liver
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The disease more frequently affects the nasal mucosa and can occur independently of its clinical form or even before lesions on the skin or on other parts of the body. It is necessary to employ epidemiological surveillance of
The synthesis and characterization of the new polyaza-phenolic-macrobicycle 32-hydroxy-1,4,7,10,13,16,19,22-octaazatricyclo-[11.11.7.1(26,30)]-diatriconta-26,28,Delta(30,32)-triene (L) are reported. L incorporates a 2,6-dimethyl-phenolic unit bridging two opposite amine functions of the [24]aneN(8)
In plant-based food, phenolic compounds usually do not exist in their native form, but as esters, glycosides, or polymers. The native forms, however, require deglycosylation for their intestinal absorption, and aglycone has been considered to be the potential health-protecting/promoting form. The
The purpose of this study was to obtain information about the detailed histopathology of naturally occurring root caries. Fifty extracted human teeth exhibiting some degree of root caries were sectioned longitudinally and examined with transmitted light, polarized light and microradiography. The