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retinoic acid/التهاب
يتم حفظ الارتباط في الحافظة
الصفحة 1 من عند 22 النتائج
Reversing intestinal inflammation by inhibiting retinoic acid metabolism
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
Reversing intestinal inflammation by inhibiting retinoic acid metabolism
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
Reversing intestinal inflammation by inhibiting retinoic acid metabolism
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
This invention relates to novel compositions-of-matter, methods for their manufacture, pharmaceutical formulations thereof and the method of using said formulations in the treatment and control of acne vulgaris.
More specifically, this invention relates to novel retinoic acid
Substituted 2,3-dihydro-1H-inden-1-one Retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
Topical treatment of non-inflammatory acne
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
The present invention relates to a method of treating noninflammatory acne.
Acne vulgaris is a common dermatological disorder which affects large patient populations in the preadolescent, adolescent and young adult age groups. Since it occurs primarily in the face and
Method of treating musculoskeletal and connective tissue inflammations
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD OF THE INVENTION
The present invention relates to a method for treatment of musculoskeletal and connective tissue inflammations. More specifically, the method utilizes 13 cis-retinoic acid to effectively treat musculoskeletal and connective tissue inflammations including osteoarthritis and
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority to the PCT Application PCT/EP2015/067713 filed on 31 Jul. 2015 which further claims the priority of Swedish Patent Application No. SE 2014/0051406 filed on 21 Nov. 2014 in the Sweden Patent and Trademark Office, and Swedish
Prevention and treatment of inflammatory conditions
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND
Field
The present embodiments relate to compositions and methods for modulating Retinoic Acid Receptor (RAR) in the prevention and treatment of inflammatory conditions of the liver.
Description of the Related Art
Excessive alcohol use is a major cause of liver disease in the Western
Particle formulations of all-trans retinoic acid and transforming growth factor beta for the treatment of type 1 diabetes mellitus
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
FIELD
The invention concerns particle formulations of all-trans retinoic acid and transforming growth factor beta for the treatment of autoimmune diseases, such as type I diabetes mellitus. Methods of making and using the particle formulations are also disclosed.
BACKGROUND
Autoimmune diseases may
Indazole and indole derivatives as inhibitors of retinoic acid related orphan receptor gamma (ROR gamma) for the treatment of immune-related diseases
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a 35 U.S.C. .sctn. 371 national phase application from, and claims priority to, International Application No. PCT/GB2015/053183, filed Oct. 23, 2015, and published under PCT Article 21(2) in English, which claims priority to GB
Psoriasis treatment with retinoic acid analogs
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
1. Field of the Invention
A wide variety of skin diseases are characterized by abnormal metabolic processes. Two classes of these conditions are the seborrheic dermatoses--which are typified by excessive secretion or disturbed quality of sebum, abnormal intercellular
Acne and psoriasis treatment with retinoic acid analogs
يمكن للمستخدمين المسجلين فقط ترجمة المقالات
الدخول التسجيل فى الموقع
BACKGROUND OF THE INVENTION
1. Field of the Invention
A wide variety of skin diseases are characterized by abnormal metabolic processes. Two classes of these conditions are the seborrheic dermatoses--which are typified by excessive secretion or disturbed quality of sebum, abnormal intercellular
قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم
- يعمل في 55 لغة
- العلاجات العشبية مدعومة بالعلم
- التعرف على الأعشاب بالصورة
- خريطة GPS تفاعلية - ضع علامة على الأعشاب في الموقع (قريبًا)
- اقرأ المنشورات العلمية المتعلقة ببحثك
- البحث عن الأعشاب الطبية من آثارها
- نظّم اهتماماتك وابقَ على اطلاع دائم بأبحاث الأخبار والتجارب السريرية وبراءات الاختراع
اكتب أحد الأعراض أو المرض واقرأ عن الأعشاب التي قد تساعد ، واكتب عشبًا واطلع على الأمراض والأعراض التي تستخدم ضدها.
* تستند جميع المعلومات إلى البحوث العلمية المنشورة
