الصفحة 1 من عند 76 النتائج
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of immunology and the biochemistry of biological response modifiers. More specifically, the present invention relates to a novel method for the inhibition of tumor necrosis factor and nitric
FIELD OF THE INVENTION
The present invention relates to the diagnosis of breast cancer. It discloses the use of cellular retinoic acid binding protein II in the diagnosis of breast cancer. Furthermore, it especially relates to a method for diagnosis of breast cancer from a liquid sample, derived
FIELD OF THE INVENTION
This invention is in the field of prevention and treatment of cancer. More specifically, this invention relates to the use of 9-cis-retinoic acids and derivatives thereof for treating cancers, in particular breast cancer. This invention also relates to the use of combinations
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of molecular biology of cancers. More specifically, the present invention relates to a method of transcription therapy for cancers.
2. Description of the Related Art
Acute promyelocytic
TECHNICAL FIELD
The present invention relates to a tumor-specific promoter that permits the expression of foreign genes in tumor cells or tumor tissues in a tumor-specific manner. More specifically, it relates to a tumor-specific promoter that enables a high transcriptional activity in tumor cells
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to dermal uses of non-irritating retinoids and particularly to dermal uses of the esters and amides of certain stereoisomers of retinoic acid.
2. Description of the Prior Art
Chronic sun exposure has been determined to
BACKGROUND OF THE INVENTION
TECHNICAL FIELD
The present invention relates to the field of 9-cis retinoic acid and its esters and amides, and particularly to their uses for a variety of therapeutic and prophylactic treatments of the skin. The present invention particularly relates to 9-cis-retinoic
DESCRIPTION
1. Technical Field
The invention is in the fields of retinoid chemistry and chemotherapy. More particularly, the invention relates to certain aromatic retinoic acid analogues.
2. Background Art
The progressive loss of the regulation of cellular differentiation by epithelial cells can
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
BACKGROUND OF THE INVENTION
Pathological inflammation is emerging as an underlying mechanism for numerous diseases. For example, the major forms of idiopathic IBD, ulcerative colitis and Crohn's disease are chronic inflammatory disorders of the gastrointestinal tract. Animal studies have shown that
DESCRIPTION
1. Technical Field
The invention is in the fields of retinoid chemistry and chemotherapy and relates to retinoic acid analogues. More particularly, the invention relates to certain retinoic acid analogues with open ring modifications.
2. Background Art
The progressive loss of the
DESCRIPTION
1. Technical Field
The invention is in the fields of retinoid chemistry and chemotherapy. More particularly, the invention relates to certain naphthenic and heterocyclic retinoic acid analogues.
2. Background Art
The progressive loss of the regulation of cellular differentiation by
REFERENCE TO GOVERNMENT GRANT OR CONTRACT
The invention described herein was made in the course of work under grant or contract from the National Institute of Health.
DESCRIPTION
1. Technical Field
The invention is in the fields of retinoid chemistry and chemotherapy. More particularly, the
BACKGROUND
For years, the cornerstones of cancer treatment have been surgery, chemotherapy, and radiation therapy. Over the last decade, targeted therapies--drugs that target cancer cells by homing in on specific molecular changes seen primarily in those cells--have also emerged as standard