Participants will be submitted to 45 minutes of exercise on ergocycle.

Sickle Cell Trait

Environmental Exposure

Adverse Effect

The exercise includes 15 minutes of warm up, then participants will be asked to pedal as fast as possible for 6 seconds. The test of 6 seconds will be repeated twice or more with recovery each time

Exercise on ergocycle

ACTES laboratory

Sickle Cell Trait and Exercise, Effect of Hot Environment

Metabolic and Vascular Response to Exercise in Sickle Cell Trait Carriers: Effect of Hot Environment

Reactive hyperemia index (arbitrary units) will be assessed at rest, during exercise and during recovery in hot and thermoneutral environment

All autors have to discuss together before to decide

Sophie Antoine-Jonville

Director

University of the French West Indies and French Guiana

Institut National de la Santé Et de la Recherche Médicale, France

All participants in each group (AA, AS) will carry out the following 3 sessions:
Exercise performed in hot environment (33 °C) with recovery in the same environment
Exercise and recovery performed in a control (thermoneutral) environment (22 °C),
Exercise performed in a hot environment (33 °C) with recovery in a thermoneutral, environment (22 °C).

sickle cell trait/carbohydrate

Sickle Cell Trait and Exercise, Effect of Hot Environment

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