There are presented compounds of the formula ##STR00001## or a pharmaceutically acceptable salt thereof, which are active adenosine A2B receptor antagonists and useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea.

Hoffmann-La Roche Inc.

Substituted thiazolo[5,4-d]pyrimidine urea derivatives

Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

Merck Frosst Canada, Inc.

Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

urea/إسهال

Substituted thiazolo[5,4-d]pyrimidine urea derivatives

Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

قاعدة بيانات الأعشاب الطبية الأكثر اكتمالا التي يدعمها العلم