9 النتائج
SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinone carboxamides and derivatives thereof of formula I,
##STR00002##
Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinonecarboxamides and derivatives thereof of formula 1,
##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
FIELD OF THE INVENTION
The present invention relates to sulfonamide derivatives, to the process for preparing them and to their therapeutic use.
BACKGROUND OF THE INVENTION
Orexins A and B (or hypocretins 1 and 2) are hypothalamus neuropeptides of 33 and 28 amino acids, respectively, recently
FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
This application is a 371 of PCT/GB93/02130, Oct. 14, 1993.
This invention relates to novel compounds having pharmacological activity, to a process for their preparation and to their use as pharmaceuticals.
European Journal of Pharmacology 146 (1988 ), 187-188, and Naunyn-Schmiedeberg's Arch.
FIELD OF THE INVENTION
The invention pertains to the field of treating patients suffering from various disorders related to various cognitive disorders. More particularly, the invention pertains to alleviating or at least improving upon adverse effects of excessive acetylcholine including, but not
FIELD OF THE INVENTION
The invention pertains to the field of treating patients suffering from various disorders related to various cognitive disorders. More particularly, the invention pertains to alleviating or at least improving upon adverse effects of excessive acetylcholine including, but not