[Effect of intravenous glucose load on blood glucose and fructose level and glucose-6-phosphate isomerase activity in serum of patients with acute cerebrovascular disease in its earliest phase].

The purpose of the study was to investigate the dynamics of glucose and fructose concentrations in the blood changes and phosphohexose isomerase activity (PHI) in serum of unfed or after intravenous glucose injection patients, with acute cerebrovascular disease in the earliest period of illness. The investigation was done in 15 patients with transient ischaemic attacks, 30 patients with cerebral ischaemic stroke and 15 patients with cerebral haemorrhage. In patients with different forms of acute cerebrovascular damage it was found that there was hyperglycaemia in the blood of unfed patients, elevated blood fructose level and increased serum PHI activity; those changes were increased by intravenous glucose administration. The changes were most expressed in the group of patients with cerebral haemorrhage and cerebral ischaemic stroke.