Pharmacological study of uzarigenin-glucoside-canaroside.

Uzarigenin-glucoside-canaroside (UGC) is a steroid glycoside isolated from the leaves of ISOPLEXIS CHALCANTHA whose pharmacological properties have not been so far studied. In this paper the effect of UGC on isolated auricle of rabbits, urinary excretion of rats, isolated jejunum of rabbits, (86)Rb (+) uptake by erythrocytes as well as its emetic effect in pigeons are presented, using digoxin as standard. The pharmacological activity of UGC was similar to that of digoxin, UGC possessing, however, a lesser vomiting action.