5 вынікі
FIELD OF THE INVENTION
This invention relates to compositions comprising a norepinephrine precursor, such as L-tyrosine or L-phenylalanine in combination with a norepinephrine re-uptake inhibitor such as desipramine. The compositions are useful in controlling obesity, depression, drug abuse, and
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates generally to certain peptides and to methods and pharmaceutical compositions incorporating such peptides, for treating mammals to control appetite and obesity.
2. Description of the Prior Art
Obesity is a well established
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates generally to certain peptides and to methods and pharmaceutical compositions incorporating such peptides, for treating mammals to control appetite and obesity.
2. Description of the Prior Art
Obesity is a well established
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted electronically in ASCII format and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Mar. 7, 2014, is named 204257-0016-WO-00(509186)_SL.txt and is 2,597 bytes in size.
The
BACKGROUND OF THE INVENTION
Agents acting at central cholecystokinin (CCK) receptors may induce satiety (Schick, Yaksh and Go, Regulatory Peptides 14:277-291, 1986). They are also expected to act as analgesics (Hill, Hughes and Pittaway, Neuropharmacology 26:289-300, 1987), and as anticonvulsants