Milk Proteins and Micronutrient Supplementation in Obese Children
Ключови думи
Резюме
Описание
Obese children were selected in elementary schools from 5 rural communities of the State of Querétaro. One hundred fifty two obese children (Z-score >2 standard deviations) aged 6-11y were randomly assigned to receive one of two treatments: 1) 237mL/day of milk proteins and multiple micronutrients supplement (MPMS) plus Nutrition Education (NE) program or 2) NE alone for 24 weeks.
Children in both groups were evaluated at baseline and 6 months after treatment initiated. At both times the following variables were evaluated:
Visit 1 (Screening): Mothers and parents received oral and written information regarding all aspects of the study. Informed consent, medical history, demographic information, weight and height were obtained.
Visit 2 (Clinical Laboratory testing): A blood preasure and sample was taken by an specialist. Blood test included Glucose, total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol, Tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6) and interleukin-10 (IL-10), C reactive protein, insulin and leptin.
Visit 3 (Nutrition Clinic at UAQ): body composition was determined by DEXA. The NE were given at Nutrition Clinic and school to the children's parents each week.
Дати
| Последна проверка: | 02/29/2020 |
| Първо изпратено: | 02/27/2020 |
| Очаквано записване подадено: | 03/22/2020 |
| Първо публикувано: | 03/23/2020 |
| Изпратена последна актуализация: | 03/22/2020 |
| Последна актуализация публикувана: | 03/23/2020 |
| Действителна начална дата на проучването: | 12/04/2011 |
| Приблизителна дата на първично завършване: | 12/04/2012 |
| Очаквана дата на завършване на проучването: | 12/04/2012 |
Състояние или заболяване
Интервенция / лечение
Dietary Supplement: Supplement with micronutrients
Other: Nutrition education
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Experimental: Supplement with micronutrients Nutrition education with a supplement | Dietary Supplement: Supplement with micronutrients Obese children were divided in 2 groups. A group received the supplement plus nutrition education and other group was a control, only received nutrition education. |
| Experimental: Nutrition education Group received only nutrition education | Other: Nutrition education Group received nutrition education program during 6 months |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 6 Years Да се 6 Years |
| Полове, допустими за проучване | All |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: - Children with obesity (BMI>30) - Aged: 6 to 11 years - Both sex - Parents accepted to participate and signed informant consent Exclusion Criteria: - Children with dyslipidemia - Metabolic disease - Hypertension - Physical disability - Using vitamins and minerals supplements and/or receiving treatment for obesity during the last 3 months. |
Резултат
Първични изходни мерки
1. Total body fat [baseline to 6 months]
Вторични изходни мерки
1. Total cholesterol [Beaseline to 6 months]
2. HDL [Baseline to 6 months]
3. LDL [baseline to 6 months]
4. Triglycerides [baseline to 6 months]
5. Glucose [baseline to 6 months]
6. Interleukin 6 (IL-6) [baseline to 6 months]
7. Interleukin 10 (IL-10) [baseline to 6 months]
8. C reactive protein (CRP) [baseline to 6 months]
9. Bone mineral density (BMD) [baseline to 6 months]
10. Body mass index (BMI) [Baseline to 6 months]
11. Zinc levels [baseline to 6 months]
12. Iron levels [baseline to 6 months]
13. A vitamin levels [baseline to 6 months]
14. C vitamin levels [baseline to 6 months]
15. D vitamin levels [baseline to 6 months]
16. E vitamin levels [baseline to 6 months]
17. Systolic blood pressure (SBP) [baseline to 6 months]
18. Diastolic blood pressure (DBP) [baseline to 6 months]
