Pharmaceutica acta Helvetiae 1989
Anti-ulcer activity of procyanidins preparation of water-soluble procyanidin-cimetidine complexes.
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The anti-ulcer properties of water-soluble procyanidins prepared by fermentation of tannins from Fragaria vesca were studied. Complexes of procyanidins and cimetidine were prepared. The procyanidins increased the water-solubility of the cimetidine and may prevent undesirable nitrosamine formation in the stomach as they block its cyanamide function.