OncoImmunology 2013-Jun
Catechins and antitumor immunity: Not MDSC's cup of tea.
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Numerous laboratory and clinical studies have reported that the green tea catechin extract Polyphenon E exert anticancer activity, but the underlying mechanism of action was elusive. We have recently shown that Polyphenon E exerts antineoplastic effects by antagonizing tumor-induced myeloid derived suppressor cells (MDSCs).