[Changes in the microcirculatory bed of the compact substance of bones following local mechanical pressure, gravitational stress and hypokinesia].

Effects of different stimuli upon the structure of the microcirculatory bed of the compact substance of long tubular bones were studied in 89 animals (rabbits and cats). Prolonged local pressure on the bone resulted in transformations characterized by lacunar resorption of the compact substance in the site of application of the force and endosteal bone-formation on the opposite side of the same part of the bone. Hypergravitation caused a considerable transformation of the microcirculatory bed and the histoarchitectonics of the bone compact substance. Smooth and linear perivascular resorption took place around dilated vessels in osteon canals. It resulted information of resorption cavities. In addition, processes of bone formation took place. Due to effects of hypokinesia the transformation of the compact substance is of a regressive character. The fibrous structures of the bony tissue and blood vessels lose their regular orientation and acquire chaotic direction.