Zhongguo Zhongyao Zazhi 2005-Sep
[Comparative studies on pharmacological effects of the main chemical constituents of Peucedanum praeruptorum from He'nan and Jiangxi].
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OBJECTIVE
To compare the pharmacological effect of the main coumarin constituents of Peucedanum praeruptorum from Jiangxi and He'nan.
METHODS
The constituents were isolated by column chromatography on silica gel and ODS and identified by NMR and MS spectroscopic methods. The antitussive, expectorant and anti-inflammatory effects of main coumarin constituents of P. praeruptorum observed in the present study.
RESULTS
The main constituents of P. praeruptorum from both Jiangxi and He'nan showed the significant antitussive and anti-inflammatory effects without obviously expectorant effect.
CONCLUSIONS
The pharmacological effects of the main coumarin constituents of Qian-hu from Jiangxi and He'nan are similar.
