[Effect of exogenous ribose-5-phosphate on the ATP level in a cardiomyocyte culture during "metabolic ischemia" and anoxia].

Addition of ribose-5-phosphate into the incubation medium of primary culture of cardiomyocytes was shown to prevent a decrease in the ATP content under conditions of "metabolic ischemia" and anoxia. Possible mechanisms of ribose-5-phosphate participation in maintaining of the energetic status of myocardial cell in pathological conditions are discussed.