Journal of Korean Medical Science 2010-Feb
Use of aripiprazole in clozapine induced enuresis: report of two cases.
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Вход / Регистрация
Линкът е запазен в клипборда
Ключови думи
Резюме
This report describes the efficacy of combined use of aripiprazole in the treatment of a patient with clozapine induced enuresis. Aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. We speculate that aripiprazole functioned as a D2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately.