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Carbon Dioxide Guided Angiography in Endovascular Abdominal Aortic Aneurysm Repair

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INTRODUCTION: Endovascular aneurysm repair (EVAR) has lower short-term morbidity and mortality than open surgery. Intra-arterial contrast agents are an important component of successful EVAR as the tool of choice for preoperative evaluation of aortic aneurysm morphology as well as precise sizing and

FIGHT-RP 1 Extension Study

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Pilot Study: Postoperative Pain Reduction by Pre Emptive N-Acetylcysteine

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Currently approximately 240 million surgical procedures are done worldwide on a yearly basis. lnguinal hernia repair is one of the most performed surgeries in ambulatory setting. Despite currently available analgesic drugs, post surgical pain management remains challenging in this group of patients,

Induced Changes in Ventilatory Responsiveness and Altitude Exposure

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This study will determine if modulating reduction/oxidation (redox) status through a temporary increase in the blood ratio of reduced-to-oxidized glutathione (i.e., GSH/GSSG) will increase carotid body chemosensitivity and thus increase ventilation and arterial oxygen saturation (SaO2) during 32

Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects

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In this study the investigators test the following hypotheses: 1. NAC causes dose-dependent vasodilatation associated with histamine release in vivo. 2. Release of other mediators, known to be associated with anaphylaxis, does not occur during anaphylactoid reactions to NAC. 3. Paracetamol has a

N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder

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N-acetylcysteine (NAC) for Children With Tourette Syndrome

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Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning Study (SNAP)

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Paracetamol is the commonest poison seen in the United Kingdom and is present in approximately 40% of patients admitted with self harm. Current treatment involves use of the antidote acetylcysteine in patients deemed at risk of potential liver damage. This is given by intravenous infusion over a

Compare Methadone Combined With N-Acetyl-Cysteine (NAC) and Methadone Alone for Opioids Astaining

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Material abuse nowadays become a serious public health issue, among these, abusing of opioids is the most serious one. It cause HIV infection rate hiking up, recent years in Taiwan, it impairing people health as well. The successive 2 year methadone substitutive abstaining program makes HIV

Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material

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In this study we will test the hypothesis that acetylcysteine exerts a renoprotective effect in RCIN by an antioxidant and/or renal vasodilator mechanism. We will take a structured 4-part approach, using randomised controlled cross-over studies to assess the effect of acetylcysteine on renal

High-Dose N-Acetylcysteine in Cardiac Surgery

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Background Renal impairment following cardiopulmonary bypass is common. 11.4% (1) to 42% (2) of patients with previously normal renal function show a postoperative rise in serum creatinine. While most of these patients do not require either short or long term renal replacement, the mortality of

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