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benzaldehyde/треска
Линкът е запазен в клипборда
14 резултата
Differential enhancement of cytotoxicity by combination of the carcinostatic agent benzaldehyde and hyperthermia in simian virus 40-transformed and normal cell lines.
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The effect of the carcinostatic drug benzaldehyde (BA) on hyperthermia-induced cytotoxicity was studied in various types of cultured mammalian cell lines by colony formation assay. The treatment of HeLa cells with nontoxic doses of BA (1 to 4 mM) at 42 and 43 degrees for up to 3 hr induced
Vaginal administration of a single dose of 16, 16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester for pre-operative cervical dilatation in first trimester nulliparae.
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A single pessary containing 0-5 mg 16, 16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester was used for cervical dilatation prior to vacuum aspiration in 124 first trimester nulliparae. Five hours after prostaglandin administration the cervix had dilated to 8 mm or more in 87 patients
Termination of pregnancy with vaginal administration of 16, 16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester.
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A 16,16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester was used for termination of pregnancy in 54 late first trimester and second trimester patients. The drug (750 microng in gelatine glycerine pessaries) was administered every four hours. Fifty patients (92-5%) aborted during the 36
Cervical dilatation with 16,16 dimethyl PGE2 p-benzaldehyde semicarbazone ester prior to vacuum aspiration in first trimester nulliparae.
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The efficacy of 16,16 dimethyl PGE2 p-benzaldehyde semicarbazone ester for cervical dilatation prior to evacuation of the uterus in 180 first trimester nulliparae has been studied. The drug was injected into the muscle of the cervix 3 hours before vacuum aspiration. In 143 patients (80%) the cervix
[Biological bases of cancer treatment by hyperthermia].
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There is little difference in heat sensitivity in vitro between normal and cancer cells. However, rather selective tumor destruction is induced by in vivo heating without affecting normal tissues. This selective effect may be attributed to heat-induced vascular damage causing reduction in the supply
Design, synthesis, acetylcholinesterase inhibition and larvicidal activity of girgensohnine analogs on Aedes aegypti, vector of dengue fever.
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Girgensohnine alkaloid was used as a natural model in the design and generation of new alkaloid-like α-aminonitrile series that was completed by the use of SSA-catalyzed Strecker reaction between commercial and inexpensive substituted benzaldehydes, piperidine (pyrrolidine, morpholine and
Evaluation of benzaldehyde derivatives from Morinda officinalis as anti-mite agents with dual function as acaricide and mite indicator.
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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus with 12-30% fatality rate. Despite severity of the disease, any medication or treatment for SFTS has not developed yet. One approach to prevent SFTS spreading is to control the arthropod vector
Hyperthermic and anorectic effects of oxazolidines derived from L-ephedrine in rats.
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Oxazolidines synthesized from (-) ephedrine have been proposed as potential pro-drugs, but no pharmacological data on these compounds has been yet reported. In this study, four such compounds are tested in rats for ephedrine-like activity using the hyperthermia and anorexia models. The compounds
Interdisciplinary investigation on ancient Ephedra twigs from Gumugou Cemetery (3800 B.P.) in Xinjiang region, northwest China.
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In the dry northern temperate regions of the northern hemisphere, the genus Ephedra comprises a series of native shrub species with a cumulative application history reaching back well over 2,000 years for the treatment of asthma, cold, fever, as well as many respiratory system diseases, especially
Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia.
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The primary pathophysiological event in sickling is the intracellular polymerization of deoxygenated haemoglobin S. Tucaresol (589C80;4[2-formyl-3-hydroxyphenoxymethyl] benzoic acid), a substituted benzaldehyde, was designed to interact with haemoglobin to increase oxygen affinity and has been shown
Zilascorb(2H), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma.
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Zilascorb(2H) is a benzaldehyde derivative giving rise to strong protein synthesis inhibition. It has shown antitumor activity against human malignant melanoma grown as xenografts in nude mice. The effect was manifest only after prolonged daily treatment and was quickly reversible when treatment was
Selenium, calcium channel blockers, and cancer risk--the Yin and Yang of apoptosis?
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It is increasingly clear that apoptosis plays a crucial role in the promotional phase of cancer development. Initiated pre-neoplastic clones in rat liver experience a high rate of apoptosis, and this rate has an important impact on the survival and growth of these clones. Suppression of apoptosis
Development of a theoretical model for the inhibition of nsP3 protease of Chikungunya virus using pyranooxazoles.
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Chikungunya virus (CHIKV) causes Chikungunya fever (CHIKF) and till date no effective medicine for its cure is available in market. Different research groups find various possible interactions between small molecules and non-structural proteins, viz. nsP3, one of the most important viral elements in
pH-responsive polymeric micelles self-assembled from benzoic-imine-containing alkyl-modified PEGylated chitosan for delivery of amphiphilic drugs
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In order to efficiently promote loading efficiency and aqueous photostability of indocyanine green (ICG), an amphiphilic tricarbocyanine dye, the polysaccharide-based nanomicelles utilized as a vehicle for ICG were fabricated by self-assembly of the amphiphilic benzoic-imine-containing PEGylated
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