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biphenyl/кръвоизлив

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СтатииКлинични изследванияПатенти
Страница 1 от 46 резултата
Outbred albino (CD-1) mice were given the following biphenyl isomers by gavage in cottonseed oil on Days 6-15 of gestation: 4,4'-dichlorobiphenyl (DCB) at 16, 32, and 64 mg/kg/day; 3,3',4,4'-tetrachlorobiphenyl (3,4-TCB) at 1,2,4,8,16,32, and 64 mg/kg/day; 3,3',5,5'-tetrachlorobiphenyl (3,5-TCB) at

Serum levels of polychlorinated biphenyls and stroke risk among Chinese: a hospital-based case-control study

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Previous studies have revealed the serious human health risk effects of organic pollutants-polychlorinated biphenyls (PCBs). However, the roles of circulating PCBs on stroke risk have not been elucidated. The purpose of this study was to examine whether serum PCBs could increase the risk for stroke

Tissue distribution of polychlorinated biphenyls (Aroclor 1254) in cockerels: relation to the duration of exposure and observations on pathology.

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Day old cockerels were given a ration containing 500 ppm of polychlorinated biphenyls (PCB) as Aroclor 1254. Mortality was recorded and various tissues analyzed for PCB levels. Tissue concentrations of PCB increased in direct relation with the time of the experiment and with the survival period of

Evaluation of ionic liquid gas chromatography stationary phases for the separation of polychlorinated biphenyls.

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The feasibility of six ionic liquid- (IL-) based stationary phases for the analysis of environmentally important polychlorinated biphenyls (PCBs) by gas chromatography combined with either electron capture micro-detector (GC-micro-ECD) or quadrupole mass spectrometry (GC-MS, for confirmation) have

Pathology of experimentally induced polybrominated biphenyl toxicosis in pregnant heifers.

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Toxicosis was induced in pregnant Holstein-Friesian heifers by giving polybrominated biphenyls a in gelatin capsules at the rate of 25 g/day. Initially, this dosage was approximately 67 mg/kg of body weight. Clinical signs were anorexia, excessive lacrimation and salivation, diarrhea, emaciation,

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa.

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BMS-654457 ((+) 3'-(6-carbamimidoyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro-quinolin-2-yl)-4-carbamoyl-5'-(3-methyl-butyrylamino)-biphenyl-2-carboxylic acid) is a small-molecule factor XIa (FXIa) inhibitor. We evaluated the in vitro properties of BMS-654457 and its in vivo activities in rabbit models

Inhibition of hepatic toxicities from polybrominated biphenyls and aflatoxin B in rats fed cauliflower.

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Feeding diets containing cauliflower to rats inhibited hepatic residues of polybrominated biphenyls (PBB) with a reduction of fatty livers produced by 50 ppm of dietary PBB. Cauliflower diets also reduced the toxic effects of aflatoxin in Fischer rats, i.e. prevented mortality and internal

Menstrual effects among women exposed to polychlorinated biphenyls and dibenzofurans.

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BACKGROUND Polychlorinated biphenyls (PCBs), dibenzofurans (PCDFs), and dibenzo-dioxins (PCDDs) may affect the female reproductive system in humans. A mass poisoning occurred in Taiwan due to PCBs/PCDFs-contaminated cooking oil, and was called the Yucheng (oil-disease in Chinese). We aimed to

Experimental polychlorinated biphenyl toxicosis in germfree pigs.

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The effects of polychlorinated biphenyls were studied in eight germfree pigs. Beginning at fourteen days of age, two pigs each were fed daily 12.5, 25, 50 and 100 mg/kg body weight of polychlorinated biphenyls as Aroclor 1254. Three germfree pigs were negative controls. Clinically the treated pigs

Dietary effects of polychlorinated biphenyls on mink.

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Poisoning occurred in 32 mink fed diets containing meat from cows which had been fed a polychlorinated biphenyl (PCB), Aroclor 1254. No live kits were produced and all adult mink died during a 105 day period of feeding a ration containing 3.57 ppm of PCB. At a level of 0.64 ppm of PCB in ration one

Assessment of ionic liquid stationary phases for the determination of polychlorinated biphenyls, organochlorine pesticides and polybrominated diphenyl ethers.

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Five ionic liquid stationary phases were tested for the gas chromatographic (GC) analysis of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In comparison with a non-polar DB5MS stationary phase, which is normally used in single-column GC for these compounds, all phases tested

Toxic equivalency factors of polybrominated dibenzo-p-dioxin, dibenzofuran, biphenyl, and polyhalogenated diphenyl ether congeners based on rainbow trout early life stage mortality.

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Polybrominated and polychlorinated biphenyls (PBBs/PCBs), dibenzo-p-dioxins (PBDDs/PCDDs), dibenzofurans (PBDFs/PCDFs), and diphenyl ethers (PBDEs/PCDEs) are persistent, lipophilic environmental contaminants that may pose a risk to fish early life stage survival. To determine this potential risk, a

Occupational exposure to polychlorinated biphenyls in electrical workers. II. Health effects.

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Health conditions were evaluated in 80 electrical workers exposed for many years to polychlorinated biphenyl (PCB) mixtures with a 42% mean chlorine content, who had blood PCB concentrations from 41 to 1319 micrograms/kg. The clinical study was based on personal history data, physical examination,

Dietary exposure to polychlorinated biphenyls is associated with increased risk of stroke in women.

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OBJECTIVE The potentially beneficial effects of fish consumption on stroke may be modified by major food contaminants in fish. Polychlorinated biphenyls (PCBs) in particular are proposed to play a role in the aetiology of stroke. The aim of this study was to assess the association between dietary

Associations of dietary polychlorinated biphenyls and long-chain omega-3 fatty acids with stroke risk.

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Little is known about joint exposure to polychlorinated biphenyls (PCBs) and long-chain omega-3 fatty acids [eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)], through fish consumption, on cerebrovascular disease risk. To explore associations of dietary PCB exposure and EPA-DHA intake
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