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Страница 1 от 671 резултата
Posaconazole: a broad-spectrum triazole antifungal.
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Posaconazale is a new triazole drug being investigated in phase III clinical trials for the treatment and prevention of invasive fungal infections. In-vitro and in-vivo studies showed that posaconazole has broad-spectrum activity against most Candida species, Cryptococcus neoformans, Aspergillus
Doripenem monohydrate, a broad-spectrum carbapenem antibiotic.
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BACKGROUND
Doripenem monohydrate, a broad-spectrum carbapenem antibiotic, has been approved by the US Food and Drug Administration for the treatment of complicated intra-abdominal infections (cIAIs) and complicated urinary tract infections (cUTIs).
OBJECTIVE
This article reviews available
The broad treatment expectations of migraine patients.
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The objective was to define the overall treatment expectations of migraineurs. Many studies have defined the expectations of patients regarding their acute migraine treatment but little information is available regarding overall expectations. During routine first visits to the author's headache
Ceftobiprole: A novel, broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus.
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OBJECTIVE
The pharmacology, antimicrobial activity, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, and place in therapy of ceftobiprole are reviewed.
CONCLUSIONS
Ceftobiprole, a novel, broad-spectrum, parenteral cephalosporin, inhibits the cell-wall synthesis of penicillin-binding
Fahr's syndrome in Southern Tunisia: A broad spectrum of clinical and etiological features.
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OBJECTIVE
We describe the clinical and etiological profile of patients with Fahr's syndrome (FS).
METHODS
Charts of sixteen patients diagnosed with FS between 1999 and 2014 were retrospectively assessed.
RESULTS
The mean age at diagnosis was 44.68 years (11-67 years). The most main presenting
Treatment of urinary tract infections: selecting an appropriate broad-spectrum antibiotic for nosocomial infections.
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Clinical and in vitro data indicate that cefepime, a fourth-generation cephalosporin, may be a valuable addition in the treatment of serious infections. In this study, hospitalized patients with complicated and uncomplicated urinary tract infection (UTI), for which parenteral therapy was
The transfusion of neutrophil-specific antibodies causes leukopenia and a broad spectrum of pulmonary reactions.
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BACKGROUND
Antibodies to neutrophil-specific antigens are the best characterized cause of transfusion-related acute lung injury (TRALI).
METHODS
A double-apheresis platelet (PLT) component was divided and transfused into two patients. One experienced chills, rigors, and dyspnea and the other
Value and limitations of adenosine in the diagnosis and treatment of narrow and broad complex tachycardias.
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The diagnostic and therapeutic potential of intravenous adenosine was studied in 64 patients during 92 episodes of regular sustained tachycardia. In 40 patients who had narrow complex tachycardias (QRS less than 0.12 s) adenosine (2.5-25 mg) restored sinus rhythm in 25 with junctional tachycardias
The efficacy and safety of flexible-dose vardenafil (levitra) in a broad population of European men.
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BACKGROUND
In fixed-dose studies, vardenafil 5, 10, and 20mg improves erectile function in men with erectile dysfunction (ED). Here, the efficacy and tolerability of vardenafil when used in a flexible-dose regimen was assessed.
METHODS
In this multicenter trial, 323 patients randomly received
Levetiracetam in a broad population of patients with refractory epilepsy: interim results of the international SKATE trial.
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OBJECTIVE
To prospectively assess the safety and efficacy of levetiracetam in patients with uncontrolled focal epilepsy, in a common practice-based setting.
METHODS
In this phase IV, open-label, 16-week community-based study, adult patients with focal seizures initially received levetiracetam 1,000
Vardenafil is effective and well-tolerated for treating erectile dysfunction in a broad population of men, irrespective of age.
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OBJECTIVE
To assess the efficacy and safety of vardenafil in the treatment of erectile dysfunction (ED) in men of different age groups.
METHODS
In a retrospective pooled subgroup analysis of randomized, double-blind, placebo-controlled studies, men from the general population with ED received either
Value of Broad Range 16S Ribosomal RNA Gene PCR / Sequencing (Br-PCR) of CSF in the Diagnosis of Bacterial Meningitis
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Bacterial meningitis is a life-threatening condition that requires quick and definitive diagnosis. Bacterial cultures from cerebrospinal fluid (CSF) return with a negative result as treatment with antimicrobials are sometimes started before sampling of CSF can be obtained which makes isolating the
A rare anomaly of the anterior communicating artery complex hidden by a large broad-neck aneurysm and disclosed by three-dimensional rotational angiography.
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Double fenestration of the anterior communicating artery (ACoA) complex associated with an aneurysm is a very rare finding and is usually caused by ACoA duplication and the presence of a median artery of the corpus callosum (MACC). We present a patient in whom double fenestration was not associated
Vardenafil improved erectile function in a "real-life" broad population study of men with moderate to severe erectile dysfunction in Australia and New Zealand.
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BACKGROUND
Phosphodiesterase type 5 inhibitor drugs produce vasodilatation by inhibiting the breakdown of cyclic guanosine monophosphate and have proven efficacy in treating erectile dysfunction (ED).
OBJECTIVE
To evaluate the efficacy, safety, and tolerability of vardenafil in men with moderate to
Redimune NF Liquid, a ready-to-use, high-concentration intravenous immunoglobulin therapy preparation, is safe and typically well tolerated in the routine clinical management of a broad range of conditions.
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In clinical practice, intravenous immunoglobulin therapy (IVIG) is used in the management of a wide variety of medical conditions. Observational studies examining IVIG use in routine clinical practice are therefore an important means of validating findings from more strictly randomized controlled
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